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剖宫产疤痕子宫内膜异位症致透明细胞癌一例并文献复习
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Abstract:
腹壁子宫内膜异位症恶变的病例罕见，其发病机制尚未明确，利用基因检测可以为研究提供新方向，进一步完善诊断标准及治疗方案。本文报道1例腹壁子宫内膜透明细胞癌，并复习相关文献来介绍该疾病，以及了解其临床特征、诊断及鉴别诊断、治疗、预后因素，以提高该疾病的诊疗水平。
The malignant transformation of abdominal endometriosis is rare, and its pathogenesis is not yet clear. The use of genetic detection can provide a new direction for research, and further improve the diagnostic criteria and treatment plan. This paper reports a case of clear cell carcinoma of abdominal wall endometrial, reviews relevant literature to introduce the disease, and understands its clinical features, diagnosis, differential diagnosis, treatment and prognostic factors, in order to improve the level of diagnosis and treatment of this disease.
| [1] | Krawczyk, N., Banys-Paluchowski, M., Schmidt, D., Ulrich, U. and Fehm, T. (2016) Endometriosis-Associated Malignancy. Geburtshilfe und Frauenheilkunde, 76, 176-181. https://doi.org/10.1055/s-0035-1558239 |
| [2] | Sun, Y., Zhang, S., Zhang, X., Li, G., Sun, F., Wang, M., et al. (2024) AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis through Erβ. Endocrinology, 165, bqae018. https://doi.org/10.1210/endocr/bqae018 |
| [3] | Matsumoto, T., Yamazaki, M., Takahashi, H., Kajita, S., Suzuki, E., Tsuruta, T., et al. (2015) Distinct β-Catenin and PIK3CA Mutation Profiles in Endometriosis-Associated Ovarian Endometrioid and Clear Cell Carcinomas. American Journal of Clinical Pathology, 144, 452-463. https://doi.org/10.1309/ajcpz5t2poofmqvn |
| [4] | Kanto, A., Kotani, Y., Murakami, K., Miyagawa, C., Nakai, H. and Matsumura, N. (2021) A Case Report of Bladder and Intestinal Endometriosis, and the Relationship between Sex Hormone Receptor Expression and PIK3CA Mutation Analysis. BMC Women’s Health, 21, Article No. 118. https://doi.org/10.1186/s12905-021-01269-6 |
| [5] | Ijichi, S., Mori, T., Suganuma, I., Yamamoto, T., Matsushima, H., Ito, F., et al. (2014) Clear Cell Carcinoma Arising from Cesarean Section Scar Endometriosis: Case Report and Review of the Literature. Case Reports in Obstetrics and Gynecology, 2014, Article ID: 642483. https://doi.org/10.1155/2014/642483 |
| [6] | Lo Iacono, M., Monica, V., Saviozzi, S., Ceppi, P., Bracco, E., Papotti, M., et al. (2011) Aurora Kinase A Expression Is Associated with Lung Cancer Histological-Subtypes and with Tumor De-Differentiation. Journal of Translational Medicine, 9, Article No. 100. https://doi.org/10.1186/1479-5876-9-100 |
| [7] | Du, R., Huang, C., Liu, K., Li, X. and Dong, Z. (2021) Targeting AURKA in Cancer: Molecular Mechanisms and Opportunities for Cancer Therapy. Molecular Cancer, 20, Article No. 15. https://doi.org/10.1186/s12943-020-01305-3 |
| [8] | Shao, S., Wang, C., Wang, S., Zhang, H. and Zhang, Y. (2020) Hsa_circ_0075341 Is Up-Regulated and Exerts Oncogenic Properties by Sponging miR-149-5p in Cervical Cancer. Biomedicine & Pharmacotherapy, 121, Article 109582. https://doi.org/10.1016/j.biopha.2019.109582 |
| [9] | Ihnen, M., zu Eulenburg, C., Kolarova, T., Qi, J.W., Manivong, K., Chalukya, M., et al. (2013) Therapeutic Potential of the Poly(ADP-Ribose) Polymerase Inhibitor Rucaparib for the Treatment of Sporadic Human Ovarian Cancer. Molecular Cancer Therapeutics, 12, 1002-1015. https://doi.org/10.1158/1535-7163.mct-12-0813 |
| [10] | Riehle, R.D., Cornea, S. and Degterev, A. (2013) Role of Phosphatidylinositol 3,4,5-Trisphosphate in Cell Signaling. In: Capelluto, D., Ed., Lipid-Mediated Protein Signaling, Springer, 105-139. https://doi.org/10.1007/978-94-007-6331-9_7 |
| [11] | Moynahan, M.E., Chen, D., He, W., Sung, P., Samoila, A., You, D., et al. (2017) Correlation between PIK3CA Mutations in Cell-Free DNA and Everolimus Efficacy in HR+, HER2− Advanced Breast Cancer: Results from BOLERO-2. British Journal of Cancer, 116, 726-730. https://doi.org/10.1038/bjc.2017.25 |
| [12] | Levine, D.A. (2013) Integrated Genomic Characterization of Endometrial Carcinoma. Nature, 497, 67-73. https://doi.org/10.1038/nature12113 |
| [13] | The Cancer Genome Atlas Research Network (2017) Integrated Genomic and Molecular Characterization of Cervical Cancer. Nature, 543, 378-384. https://doi.org/10.1038/nature21386 |
| [14] | Levine, D.A., Bogomolniy, F., Yee, C.J., Lash, A., Barakat, R.R., Borgen, P.I., et al. (2005) Frequent Mutation of the PIK3CA Gene in Ovarian and Breast Cancers. Clinical Cancer Research, 11, 2875-2878. https://doi.org/10.1158/1078-0432.ccr-04-2142 |
| [15] | Wong, K., Engelman, J.A. and Cantley, L.C. (2010) Targeting the PI3K Signaling Pathway in Cancer. Current Opinion in Genetics & Development, 20, 87-90. https://doi.org/10.1016/j.gde.2009.11.002 |
| [16] | Janku, F., Wheler, J.J., Westin, S.N., Moulder, S.L., Naing, A., Tsimberidou, A.M., et al. (2012) PI3K/AKT/mTOR Inhibitors in Patients with Breast and Gynecologic Malignancies Harboring PIK3CA Mutations. Journal of Clinical Oncology, 30, 777-782. https://doi.org/10.1200/jco.2011.36.1196 |
| [17] | Di Nicolantonio, F., Arena, S., Tabernero, J., Grosso, S., Molinari, F., Macarulla, T., et al. (2010) Deregulation of the PI3K and KRAS Signaling Pathways in Human Cancer Cells Determines Their Response to Everolimus. Journal of Clinical Investigation, 120, 2858-2866. https://doi.org/10.1172/jci37539 |
| [18] | Zhang, C., Li, Z., Qi, F., Hu, X. and Luo, J. (2019) Exploration of the Relationships between Tumor Mutation Burden with Immune Infiltrates in Clear Cell Renal Cell Carcinoma. Annals of Translational Medicine, 7, 648-648. https://doi.org/10.21037/atm.2019.10.84 |
| [19] | Nishida, H., Kusaba, T., Kawamura, K., Oyama, Y. and Daa, T. (2023) Histopathological Aspects of the Prognostic Factors for Salivary Gland Cancers. In: Lv, W., Eds., Prime Archives in Cancer Research, Vide Leaf, 1-37. https://doi.org/10.37247/pacr3ed.3.23.4 |
| [20] | Simanjuntak, B., Jeo, W.S. and Krisnuhoni, E. (2018) Correlation between Microsatellite Instability (MSI) and 5-Year Survival in Patients with Colorectal Cancer. Journal of Physics: Conference Series, 1073, Article 042021. https://doi.org/10.1088/1742-6596/1073/4/042021 |
| [21] | Rantanen, P., Keränen, A., Barot, S., Ghazi, S., Liljegren, A., Nordenvall, C., et al. (2023) The Prognostic Significance of Microsatellite Instability in Colorectal Cancer: A Swedish Multi-Center Study. International Journal of Colorectal Disease, 38, Article No. 197. https://doi.org/10.1007/s00384-023-04480-z |
| [22] | Sampson, J.A. (1925) Endometrial Carcinoma of the Ovary, Arising in Endometrial Tissue in That Organ. Archives of Surgery, 10, 1-72. https://doi.org/10.1001/archsurg.1925.01120100007001 |
| [23] | Benoit, L., Arnould, L., Cheynel, N., Diane, B., Causeret, S., Machado, A., et al. (2006) Malignant Extraovarian Endometriosis: A Review. European Journal of Surgical Oncology, 32, 6-11. https://doi.org/10.1016/j.ejso.2005.08.011 |
| [24] | Giannini, A., Massimello, F., Caretto, M., Cosimi, G., Mannella, P., Luisi, S., et al. (2024) Factors in Malignant Transformation of Ovarian Endometriosis: A Narrative Review. Gynecological Endocrinology, 40, Article 2409911. https://doi.org/10.1080/09513590.2024.2409911 |
| [25] | Nguyen, V.H.L., Hough, R., Bernaudo, S. and Peng, C. (2019) Wnt/β-Catenin Signalling in Ovarian Cancer: Insights into Its Hyperactivation and Function in Tumorigenesis. Journal of Ovarian Research, 12, Article No. 122. https://doi.org/10.1186/s13048-019-0596-z |
| [26] | 中华医学会妇产科学分会子宫内膜异位症协作组. 子宫内膜异位症的诊治指南[J]. 中华妇产科杂志, 2015, 50(3): 161-169. |
