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炎症性肠病与肾脏疾病关系的研究进展
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Abstract:
炎症性肠病(IBD)是一组主要发生在胃肠道粘膜的慢性炎症性疾病，包括溃疡性结肠炎(UC)和克罗恩病(CD)。除了影响胃肠道，IBD还具有多种肠外表现(EIM)，其中肾脏受累是常见的并发症之一。研究表明，IBD可导致多种肾脏疾病，包括肾小球肾炎、肾小管间质性肾炎、肾结石、肾细胞癌、淀粉样变性、急性肾损伤和慢性肾脏病等。本文就IBD与肾脏疾病之间的研究进展进行综述，探讨IBD对肾脏健康的影响及其潜在机制。
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders primarily affecting the gastrointestinal mucosa, including ulcerative colitis (UC) and Crohn’s disease (CD). In addition to gastrointestinal involvement, IBD is associated with various extraintestinal manifestations (EIM), with renal involvement being one of the common complications. Studies have shown that IBD can lead to multiple kidney diseases, including glomerulonephritis, interstitial nephritis, kidney stones, renal cell carcinoma, amyloidosis, acute kidney injury, and chronic kidney disease. This article reviews the research progress on the relationship between IBD and kidney diseases, exploring the impact of IBD on renal health and its potential mechanisms.
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