加味半夏泻心汤联合四联治疗脾胃湿热型幽门螺杆菌相关性慢性胃炎40例临床疗效观察
Observation on the Clinical Efficacy of Added Banxia Xiexin Decoction and Quadruple Drug Therapy in the Treatment of 40 Cases of Chronic Gastritis Associated with Hp-Related Chronic Gastritis with Spleen Stomach Damp

目的：探究加味半夏泻心汤联合四联疗法治疗幽门螺杆菌(Hp)相关性慢性胃炎脾胃湿热型的临床疗效。方法：将2022年7月~2024年7月随州市中医医院脾胃病科科诊治的40例Hp感染后脾胃湿热型慢性胃炎患者作为研究对象，随机将研究对象分为对照组(四联疗法)和研究组(四联疗法合用加味半夏泻心汤)，每组各20例。观察两组患者临床症状治疗有效率、Hp根除率及中医证候积分的变化情况。结果：研究组(四联疗法合用加味半夏泻心汤组)证候治疗有效率、Hp根除率均高于对照组(四联疗法组)，差异有统计学意义(P < 0.05)；研究组(四联疗法合用加味半夏泻心汤组)上述指标均低于对照组(四联疗法组)，差异有统计学意义(P < 0.05)。结论：在Hp相关性脾胃湿热型慢性胃炎的治疗中，加味半夏泻心汤联合四联疗法能更好地根除Hp，能快速改善患者相关临床证候，提高其日常生活质量，经济高效，疗效可靠。
Objective: To explore the clinical efficacy of modified Banxia Xiexin Tang combined with quadruple therapy in the treatment of Helicobacter pylori (Hp)-related chronic gastritis with spleen stomach damp heat type. Methods: Forty patients with chronic gastritis of spleen and stomach damp heat type after Hp infection treated by the type of Spleen and Stomach Diseases from July 2022 to July 2024 were selected as the study subjects. The study subjects were randomly divided into a control group (quadruple therapy) and a study group (quadruple therapy combined with modified Banxia Xiexin Tang), with 20 cases in each group. Observe the changes in the effective rate of clinical symptom treatment, Hp eradication rate, and TCM syndrome score between two groups of patients. Results: The treatment efficacy and Hp eradication rate of the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were higher than those in the other one (the quadruple therapy group); The above indicators in the research group (the combination of quadruple therapy and modified Banxia Xiexin Tang group) were lower than those in the other group (quadruple therapy group), the difference was statistically significant (P < 0.05). Conclusion: In the treatment of Hp related spleen stomach damp heat chronic gastritis, the combination of modified Banxia Xiexin Tang and quadruple therapy can better eradicate Hp, rapidly improve patients' relevant clinical symptoms, enhance their quality of life, and have reliable therapeutic effects. It is recommended for application.