Objective: To explore the effectiveness of OSCE-based Escape Room Approach for nursing training in the Department of Gastroenterology. Method: 160 nursing students who were interns in the Department of Gastroenterology of the Affiliated Hospital of Xuzhou Medical University were enrolled and randomly divided into the experimental group and the control group, with 80 participants in each group. Conventional approach and the Escape Room Approach were employed for the experimental group and the control group, respectively. Result: The critical thinking capability, learning engagement, scores of self-regulated learning capability of clinical nursing practice and final scores of the experimental group were significantly higher than those of the control group (P < 0.05). Conclusion: OSCE-based Escape Room Approach can effectively enhance critical thinking capability, learning engagement, scores of self-regulated learning capability of clinical nursing practice, and knowledge and skills of the nursing interns.
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