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电腹针联合承气逐瘀汤灌肠治疗脓毒症(热毒瘀阻证)的临床疗效观察
Clinical Observation on the Therapeutic Effect of Electro Abdominal Acupuncture Combined with Chengqi Zhuyu Decoction Enema in the Treatment of Sepsis (Heat Toxicity and Blood Stasis Syndrome)

DOI: 10.12677/acm.2024.1492602, PP. 1334-1340

Keywords: 电腹针,承气逐瘀汤,中药灌肠,脓毒症
Electroacupuncture
, Chengqi Zhuyu Decoction, Chinese Medicine Enema, Pyemia

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Abstract:

目的:探讨电腹针联合承气逐瘀汤灌肠治疗脓毒症(热毒瘀阻证)胃肠功能障碍患者的治疗效果。方法:将60例脓毒症(热毒瘀阻证)患者用中央随机系统分为观察组、对照组,每一组包含30名患者,两组在年龄、性别以及APACHEII评分方面都没有显示出统计学上的显著差异(P > 0.05)。对照组参考脓毒症治疗指南给予常规治疗和护理,观察组于常规治疗护理基础上加用电腹针联合承气逐瘀汤灌肠治疗,7 d为1个疗程。观察并比较两组施治前后的肠鸣音、腹围、APACHEII评分、SOFA评分、WBC、CRP、PCT等相应指标。结果:治疗7 d后两组主要指标均较前改善(P < 0.05),观察组优于对照组(P < 0.05)。观察组综合有效率为90.00%高于对照组的71.67% (P < 0.05)。结论:在常规治疗和护理基础上给予电腹针联合承气逐瘀汤灌肠对脓毒症(热毒瘀阻证)患者的临床疗效优于常规西医治疗,其机制可能与脓毒症患者邪热与糟粕互结,形成燥屎而阻于肠道相关。电腹针联合中药灌肠有助于排泄肠道糟粕,防止毒素及炎性介质蓄积,进而改善胃肠功能障碍。
Objective: To explore the therapeutic effect of electro abdominal acupuncture combined with Chengqi Zhuyu Decoction enema in the treatment of patients with sepsis (heat toxicity and blood stasis syndrome) and gastrointestinal dysfunction. Method: Sixty patients with sepsis (heat toxin stasis syndrome) were divided into observation group and control group by central randomized system, with 30 patients in each group. There were no statistically significant differences in age, gender and APACHEII scores between the two groups (P > 0.05). The control group was given routine treatment and nursing according to the treatment guidelines for sepsis, and the observation group was treated with electro abdominal acupuncture combined with Chengqi Zhuyu Decoction on the basis of conventional treatment and nursing, with a course of 7 days. Intestinal sound, abdominal circumference, APACHE II score, SOFA score, WBC, CRP, PCT and other relevant indexes were observed and compared between the two groups before and after treatment. Result: After 7 days of treatment, the main indicators of both groups improved compared to before (P < 0.05), and the observation group was better than the control group (P < 0.05), and the observation group was better than the control group (P < 0.05). The comprehensive effective rate of the observation group was 90.00% higher than that of the control group (71.67%) (P < 0.05). Conclusion: On the basis of conventional treatment and nursing, electric abdominal acupuncture combined with Chengqi Zhuyu Tang enema has a better clinical effect than conventional western medicine in patients with sepsis (heat toxin stasis syndrome). The mechanism may be related to the information of pathogenic heat and dregs in patients with sepsis, which forms dry feces and obstructs the intestine. Electro abdominal acupuncture combined with Chinese medicine enema can help to excrete intestinal dross, prevent the accumulation of toxins and inflammatory mediators, and improve

References

[1]  Bauer, M., Singer, M., Opal, S.M., et al. (2013) The Third International Consensus Definitions for Sepsis and Septic Shock.
[2]  Shankar-Hari, M., Phillips, G.S., Levy, M.L., Seymour, C.W., Liu, V.X., Deutschman, C.S., et al. (2016) Developing a New Definition and Assessing New Clinical Criteria for Septic Shock. Journal of the American Medical Association, 315, 775-787.
https://doi.org/10.1001/jama.2016.0289
[3]  Seymour, C.W., Liu, V.X., Iwashyna, T.J., Brunkhorst, F.M., Rea, T.D., Scherag, A., et al. (2016) Assessment of Clinical Criteria for Sepsis. Journal of the American Medical Association, 315, 762-774.
https://doi.org/10.1001/jama.2016.0288
[4]  吴凡伟, 周仙仕, 叶烨. 针刺治疗脓毒症机理研究进展[J]. 国际中医中药杂志, 2016, 38(11): 1046-1049.
[5]  曹钰, 柴艳芬, 邓颖, 等. 中国脓毒症/脓毒性休克急诊治疗指南(2018) [J]. 感染.炎症.修复, 2019, 20(1): 3-22.
[6]  中华医学会急诊医学分会危重病专家委员会, 中国中西医结合学会急救医学专业委员会. 脓毒症的定义、诊断标准、中医证候诊断要点及说明(草案) [J]. 中华急诊医学杂志, 2007, 16(8): 797-798.
[7]  李乾构, 周学文, 等. 中医消化病诊疗指南[J]. 北京: 中国中医药出版社, 2006.
[8]  刘凯, 王秀珍, 王亚楠, 等. 电腹针对脓毒症并发肠屏障功能障碍的临床研究[J]. 针灸临床杂志, 2022, 38(3): 17-20.
[9]  中华人民共和国卫生部. 中药新药临床研究指导原则(试行) [M]. 北京: 中国医药科技出版社, 2002: 134-139+374.
[10]  Haak, B.W. and Wiersinga, W.J. (2017) The Role of the Gut Microbiota in Sepsis. The Lancet Gastroenterology & Hepatology, 2, 135-143.
https://doi.org/10.1016/s2468-1253(16)30119-4
[11]  天津中医学院《素问》整理研究课题组. 《黄帝内经素问》校注[J]. 天津中医药大学学报, 1985(3): 35-38.
[12]  石变, 修丽娟, 魏品康. 脓毒症患者胃肠功能障碍的中医药治疗进展[J]. 现代生物医学进展, 2011, 23(S1): 4771-4773.
[13]  彭树攀, 邱甜甜. 中药汤剂灌肠在临床治疗中的优势[J]. 黑龙江科学, 2020, 11(22): 36-37.
[14]  万学红, 卢雪峰. 诊断学[M]. 第8版. 北京: 人民卫生出版社, 2013.

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