|
|
卵圆孔未闭封堵术治疗偏头痛患者的相关研究进展
|
Abstract:
大量的研究发现偏头痛与卵圆孔未闭这两种疾病之间存在一定的关系，但关系性质尚不清晰。而引发偏头痛的病理机制也尚不确切，所以针对病因的治疗就存在一定的局限性。多项研究结果也提示，对于合并PFO的部分偏头痛患者，行PFO封堵术后临床症状得以改善，但也有研究认为介入手术的疗效优势尚不明显。本文主要从PFO与偏头痛之间的关系、两者相关的发病机制、PFO封堵术治疗偏头痛的相关研究及临床症状改善的相关因素等方面进行综述。
A large number of studies have found a certain relationship between migraine and patent foramen ovale, but the nature of the relationship is still unclear. The pathological mechanism that causes migraines is still unclear, so there are certain limitations in the treatment of the cause. Multiple research results also suggest that for some migraine patients with combined PFO, clinical symptoms can be improved after PFO occlusion surgery. However, some studies suggest that the therapeutic advantage of interventional surgery is not yet significant. This article mainly reviews the relationship between PFO and migraine, the pathogenesis of their correlation, research on PFO occlusion for migraine treatment, and factors related to clinical symptom improvement.
| [1] | Ashina, M. (2020) Migraine. New England Journal of Medicine, 383, 1866-1876. https://doi.org/10.1056/nejmra1915327 |
| [2] | Headache Classification Committee of the International Headache Society (IHS) (2018) The International Classification of Headache Disorders, 3rd Edition. Cephalalgia, 38, 1-211. |
| [3] | Del Sette, M., Angeli, S., Leandri, M., Ferriero, G., Bruzzone, G.L., Finocchi, C., et al. (1998) Migraine with Aura and Right-to-Left Shunt on Transcranial Doppler: A Case-Control Study. Cerebrovascular Diseases, 8, 327-330. https://doi.org/10.1159/000015875 |
| [4] | Carod-Artal, F., Ribeiro, L.d.S., Braga, H., Kummer, W., Mesquita, H. and Vargas, A. (2006) Prevalence of Patent Foramen Ovale in Migraine Patients with and without Aura Compared with Stroke Patients. A Transcranial Doppler Study. Cephalalgia, 26, 934-939. https://doi.org/10.1111/j.1468-2982.2006.01156.x |
| [5] | Domitrz, I., Mieszkowski, J. and Kamińska, A. (2007) Relationship between Migraine and Patent Foramen Ovale: A Study of 121 Patients with Migraine. Headache: The Journal of Head and Face Pain, 47, 1311-1318. https://doi.org/10.1111/j.1526-4610.2006.00724.x |
| [6] | Takagi, H. and Umemoto, T. (2016) A Meta-Analysis of Case-Control Studies of the Association of Migraine and Patent Foramen Ovale. Journal of Cardiology, 67, 493-503. https://doi.org/10.1016/j.jjcc.2015.09.016 |
| [7] | Wang, S., Liu, K., Yang, Y., Li, Y., Hu, M., Lin, P., et al. (2017) Prevalence and Extent of Right-to-Left Shunt on Contrast-Enhanced Transcranial Doppler in Chinese Patients with Migraine in a Multicentre Case-Control Study. Cephalalgia, 38, 690-696. https://doi.org/10.1177/0333102417708203 |
| [8] | Kahya Eren, N., Bülbül, N.G., Yakar Tülüce, S., Nazl？, C. and Beckmann, Y. (2015) To Be or Not to Be Patent: The Relationship between Migraine and Patent Foramen Ovale. Headache: The Journal of Head and Face Pain, 55, 934-942. https://doi.org/10.1111/head.12618 |
| [9] | Wilmshurst, P.T. (2017) Migraine with Aura and Persistent Foramen Ovale. Eye, 32, 184-188. https://doi.org/10.1038/eye.2017.269 |
| [10] | Khessali, H., Mojadidi, M.K., Gevorgyan, R., Levinson, R. and Tobis, J. (2012) The Effect of Patent Foramen Ovale Closure on Visual Aura without Headache or Typical Aura with Migraine Headache. JACC: Cardiovascular Interventions, 5, 682-687. https://doi.org/10.1016/j.jcin.2012.03.013 |
| [11] | Khasiyev, F., Arsava, E.M. and Topcuoglu, M.A. (2020) Cerebral Vasomotor Reactivity in Migraine: Effect of Patent Foramen Ovale and Aerogenic Microembolism. Neurological Research, 42, 795-804. https://doi.org/10.1080/01616412.2020.1775015 |
| [12] | Ashina, M., Hansen, J.M., Do, T.P., Melo-Carrillo, A., Burstein, R. and Moskowitz, M.A. (2019) Migraine and the Trigeminovascular System—40 Years and Counting. The Lancet Neurology, 18, 795-804. https://doi.org/10.1016/s1474-4422(19)30185-1 |
| [13] | Borgdorff, P. and Tangelder, G.J. (2012) Migraine: Possible Role of Shear‐induced Platelet Aggregation with Serotonin Release. Headache: The Journal of Head and Face Pain, 52, 1298-1318. https://doi.org/10.1111/j.1526-4610.2012.02162.x |
| [14] | Lopez, M.F., Sarracino, D.A., Vogelsang, M., Sutton, J.N., Athanas, M., Krastins, B., et al. (2012) Heart-Brain Signaling in Patent Foramen Ovale-Related Stroke: Differential Plasma Proteomic Expression Patterns Revealed with a 2-Pass Liquid Chromatography-Tandem Mass Spectrometry Discovery Workflow. Journal of Investigative Medicine, 60, 1122-1130. https://doi.org/10.2310/jim.0b013e318276de0e |
| [15] | Wilmshurst, P. and Nightingale, S. (2006) The Role of Cardiac and Pulmonary Pathology in Migraine: A Hypothesis. Headache: The Journal of Head and Face Pain, 46, 429-434. https://doi.org/10.1111/j.1526-4610.2006.00374.x |
| [16] | Price, M.J. (2017) Transcatheter Closure of Patent Foramen Ovale. Interventional Cardiology Clinics, 6, 555-567. https://doi.org/10.1016/j.iccl.2017.05.001 |
| [17] | Ben-Assa, E., Rengifo-Moreno, P., Al-Bawardy, R., Kolte, D., Cigarroa, R., Cruz-Gonzalez, I., et al. (2020) Effect of Residual Interatrial Shunt on Migraine Burden after Transcatheter Closure of Patent Foramen Ovale. JACC: Cardiovascular Interventions, 13, 293-302. https://doi.org/10.1016/j.jcin.2019.09.042 |
| [18] | Takizawa, T., Ayata, C. and Chen, S.P. (2020) Therapeutic Implications of Cortical Spreading Depression Models in Migraine. Progress in Brain Research, 255, 29-67. |
| [19] | Mohanty, S., Mohanty, P., Rutledge, J.N., Di Biase, L., Yan, R.X., Trivedi, C., et al. (2015) Effect of Catheter Ablation and Periprocedural Anticoagulation Regimen on the Clinical Course of Migraine in Atrial Fibrillation Patients with or without Pre-Existent Migraine: Results from a Prospective Study. Circulation: Arrhythmia and Electrophysiology, 8, 279-287. https://doi.org/10.1161/circep.114.002285 |
| [20] | Couch, J.R. and Hassanein, R.S. (1977) Platelet Aggregability in Migraine. Neurology, 27, 843-843. https://doi.org/10.1212/wnl.27.9.843 |
| [21] | Wachowicz, B. (1982) Platelet Activation: Its Possible Role in the Migraine Mechanism. Advanced Neurology, 33, 243-246. |
| [22] | Sarchielli, P., Alberti, A., Coppola, F., Baldi, A., Gallai, B., Floridi, A., et al. (2004) Platelet-Activating Factor (PAF) in Internal Jugular Venous Blood of Migraine without Aura Patients Assessed during Migraine Attacks. Cephalalgia, 24, 623-630. https://doi.org/10.1111/j.1468-2982.2003.00717.x |
| [23] | Chambers, J.B., Seed, P.T. and Ridsdale, L. (2014) Clopidogrel as Prophylactic Treatment for Migraine: A Pilot Randomised, Controlled Study. Cephalalgia, 34, 1163-1168. https://doi.org/10.1177/0333102414531156 |
| [24] | Trabattoni, D., Brambilla, M., Canzano, P., Becchetti, A., Teruzzi, G., Porro, B., et al. (2022) Migraine in Patients Undergoing PFO Closure: Characterization of a Platelet-Associated Pathophysiological Mechanism: The LEARNER Study. JACC: Basic to Translational Science, 7, 525-540. https://doi.org/10.1016/j.jacbts.2022.02.002 |
| [25] | Wilmshurst, P.T. (2004) Inheritance of Persistent Foramen Ovale and Atrial Septal Defects and the Relation to Familial Migraine with Aura. Heart, 90, 1315-1320. https://doi.org/10.1136/hrt.2003.025700 |
| [26] | 万林姗, 宋秀娟, 刘燕燕, 等. 偏头痛与卵圆孔未闭的研究进展[J]. 中国现代医学杂志, 2023, 33(10): 48-54. |
| [27] | Romano, V., Gallinoro, C.M., Mottola, R., Serio, A., Di Meglio, F.D., Castaldo, C., et al. (2021) Patent Foramen Ovale—A Not So Innocuous Septal Atrial Defect in Adults. Journal of Cardiovascular Development and Disease, 8, Article No. 60. https://doi.org/10.3390/jcdd8060060 |
| [28] | 中国医师协会神经内科医师分会, 中国研究型医院学会头痛与感觉障碍专业委员会. 中国偏头痛诊治指南(2022版) [J]. 中国疼痛医学杂志, 2022, 28(12): 881-898. |
| [29] | 国家卫生健康委员会国家结构性心脏病介入质量控制中心, 国家心血管病中心结构性心脏病介入质量控制中心, 中华医学会心血管病学分会先心病经皮介入治疗指南工作组, 等. 常见先天性心脏病经皮介入治疗指南(2021版) [J]. 中华医学杂志, 2021, 101(38): 3054-3076. |
| [30] | 何璐, 张玉顺. 单中心1336例经导管封堵卵圆孔未闭患者主要并发症回顾性分析[J]. 中国介入心脏病学杂志, 2019, 27(6): 309-314. |
| [31] | Gupta, V.K. (2004) Percutaneous Closure of Patent Foramen Ovale Reduces the Frequency of Migraine Attacks. Neurology, 63, 1760-1761. https://doi.org/10.1212/wnl.63.9.1760-a |
| [32] | Dowson, A., Mullen, M.J., Peatfield, R., Muir, K., Khan, A.A., Wells, C., et al. (2008) Migraine Intervention with Starflex Technology (MIST) Trial: A Prospective, Multicenter, Double-Blind, Sham-Controlled Trial to Evaluate the Effectiveness of Patent Foramen Ovale Closure with STARFlex Septal Repair Implant to Resolve Refractory Migraine Headache. Circulation, 117, 1397-1404. https://doi.org/10.1161/circulationaha.107.727271 |
| [33] | Mattle, H.P., Evers, S., Hildick-Smith, D., Becker, W.J., Baumgartner, H., Chataway, J., et al. (2016) Percutaneous Closure of Patent Foramen Ovale in Migraine with Aura, a Randomized Controlled Trial. European Heart Journal, 37, 2029-2036. https://doi.org/10.1093/eurheartj/ehw027 |
| [34] | Tobis, J.M., Charles, A., Silberstein, S.D., Sorensen, S., Maini, B., Horwitz, P.A., et al. (2017) Percutaneous Closure of Patent Foramen Ovale in Patients with Migraine. Journal of the American College of Cardiology, 70, 2766-2774. https://doi.org/10.1016/j.jacc.2017.09.1105 |
| [35] | Mojadidi, M.K., Kumar, P., Mahmoud, A.N., Elgendy, I.Y., Shapiro, H., West, B., et al. (2021) Pooled Analysis of PFO Occluder Device Trials in Patients with PFO and Migraine. Journal of the American College of Cardiology, 77, 667-676. https://doi.org/10.1016/j.jacc.2020.11.068 |
| [36] | Shi, Y., Lv, J., Han, X. and Luo, G. (2017) Migraine and Percutaneous Patent Foramen Ovale Closure: A Systematic Review and Meta-Analysis. BMC Cardiovascular Disorders, 17, Article No. 203. https://doi.org/10.1186/s12872-017-0644-9 |
| [37] | 贺耀德. 经导管卵圆孔未闭封堵术治疗偏头痛的远期疗效研究[D]: [硕士学位论文]. 长春: 吉林大学, 2020. |
| [38] | 荣清青. 卵圆孔未闭合并偏头痛患者行介入封堵术的疗效观察[D]: [硕士学位论文]. 济宁: 济宁医学院, 2023. |
| [39] | Liu, K., Wang, B.Z., Hao, Y., Song, S. and Pan, M. (2020) The Correlation between Migraine and Patent Foramen Ovale. Frontiers in Neurology, 11, Article ID: 543485. https://doi.org/10.3389/fneur.2020.543485 |
| [40] | Rovera, C., Biasco, L., Orzan, F., Belli, R., Omedè, P. and Gaita, F. (2014) Percutaneous Implantation of a Second Device in Patients with Residual Right‐to‐left Shunt after Patent Foramen Ovale Closure. Journal of Interventional Cardiology, 27, 548-554. https://doi.org/10.1111/joic.12162 |
| [41] | He, Q., Zhang, Y., Wang, F., Li, C., Guo, R., Li, X., et al. (2019) Impact of Right-to-Left Shunt and Transcatheter Closure on the Clinical Features of Migraine. International Journal of Neuroscience, 130, 270-275. https://doi.org/10.1080/00207454.2019.1672681 |
| [42] | Ahmed, Z. and Sommer, R.J. (2021) Reassessing the PFO-Migraine Trials. Journal of the American College of Cardiology, 77, 677-679. https://doi.org/10.1016/j.jacc.2020.12.017 |
| [43] | Zhao, Q., Liu, R., Zhou, J., Dong, Z. and Chen, Y. (2021) Prevalence and Grade of RLS in Migraine: A Prospective Study of 251 Migraineurs by Synchronous Test of c-TTE and c-TCD. Medicine, 100, e24175. https://doi.org/10.1097/md.0000000000024175 |
| [44] | 李柯柯, 杨青松, 张植, 等. 封堵术治疗青年偏头痛合并卵圆孔未闭的疗效[J]. 中国实用神经疾病杂志, 2023, 26(6): 725-730. |
| [45] | 谭永斌. 介入封堵治疗卵圆孔未闭合并偏头痛的临床研究[D]: [硕士学位论文]. 南昌: 南昌大学, 2023. |
| [46] | 黄梦婷, 李超, 刘学, 等. 经食管超声引导下介入封堵术对老年卵圆孔未闭的临床疗效观察[J]. 北京医学, 2023, 45(9): 758-762+767. |
| [47] | 高建朝, 李利利, 王登峰. 偏头痛与卵圆孔未闭的关系及介入封堵术治疗效果分析[J]. 临床心身疾病杂志, 2022, 28(1): 53-56+81. |
| [48] | 黄嘉伟, 王琼涛, 李鹏飞. 不同类型偏头痛合并卵圆孔未闭的患者行介入封堵术近中期疗效分析[J]. 中国医学工程, 2023, 31(12): 18-23. |
| [49] | 霍萍. 介入封堵术治疗伴有卵圆孔未闭偏头痛患者的效果分析[J]. 中西医结合心血管病电子杂志, 2020, 8(11): 38. |
| [50] | 胡娟, 谭利国, 王家宁. 卵圆孔未闭合并偏头痛患者介入封堵术后临床疗效观察[J]. 广东医学, 2022, 43(8): 1041-1046. |
| [51] | 刘茂林, 胡邦, 刘胜, 等. 合并偏头痛的卵圆孔未闭患者经食管超声引导下行封堵术的疗效分析[J]. 贵州医药, 2023, 47(7): 1089-1090. |
| [52] | 汪昆, 王新兰, 丁小强, 等. 高原地区介入封堵术在偏头痛合并卵圆孔未闭患者中的应用效果分析[J]. 高原医学杂志, 2023, 33(2): 23-26. |
| [53] | 梁永梅, 王霄芳, 叶文倩, 等. 卵圆孔未闭封堵术对合并隐匿性脑卒中或偏头痛患者的近中期疗效观察[J]. 中国医药, 2022, 17(9): 1335-1337. |
| [54] | 张朋飞, 庄康乐, 张锡栋, 等. 卵圆孔封堵术对偏头痛患者的近中期疗效观察分析[J]. 安徽医专学报, 2023, 22(1): 22-24. |
| [55] | 杨小彬, 张晓燕, 高红红, 等. MPV、PLT及PDW水平与卵圆孔未闭相关偏头痛患者的相关性分析[J]. 临床和实验医学杂志, 2023, 22(13): 1367-1370. |
