可变压力持续气道正压通气与固定压力持续气道正压通气治疗OSAHS患者的效果对比
Variable Pressure Continuous Positive Airway Pressure Ventilation versus Fixed Pressure Continuous Positive Airway Pressure Ventilation for the Treatment of Patients with OSAHS

睡眠呼吸暂停低通气综合征作为一种临床常见疾病，在国内外发病率日益增多。其中，阻塞性睡眠呼吸暂停低通气综合征患者的上呼吸道阻塞是由于呼吸道不同平面的解剖结构异常，引起呼吸暂停和低通气情况的发生。目前，治疗方法主要根据OSAHS的严重程度，对于轻度患者，通常予以佩戴口腔矫正器、减肥、戒烟、戒酒或者夜间保持侧卧位睡眠等保守治疗方法即可取得不错收益。对于中重度的患者，或是使用上述治疗方法无效或者效果欠佳的轻度OSAHS患者，可以选择呼吸机治疗。手术疗法也是OSAHS不可忽略的治疗手段，此种方法主要适用于中重度OSAHS患者，但目前来看，短期效果良好，长期效果欠佳，由于复发几率高，可能需要多次手术，不推荐作为一线治疗方法。目前，对于OSAHS最常用的治疗方法是正压通气，临床上最常使用的两种是AUTO-CPAP和CPAP。本研究主要是归纳总结上述两种呼吸机对于治疗OSAHS患者产生的影响有哪些不同。
Sleep apnoea hypopnoea syndrome, a common clinical disorder, is increasing in incidence both at home and abroad, and among them, the upper airway obstruction in patients with obstructive sleep apnea-hypopnea syndrome is due to the abnormalities of the anatomical structures in different planes of the airway, which ultimately causes the occurrence of apnea and hypoventilation conditions. Currently, treatment is based on the severity of OSAHS, and for mild cases, conservative treatments such as wearing an orthodontic appliance, losing weight, quitting smoking and drinking, or sleeping on the side at night can be beneficial. For patients with moderate to severe OSAHS, or for those with mild OSAHS who do not respond well to the above treatments, ventilator therapy is an option. Surgery is also a non-negligible treatment for OSAHS. This method is mainly applicable to patients with moderate to severe OSAHS, but so far, the short-term effect is good, but the long-term effect is not good, and due to the high chance of recurrence, multiple surgeries may be required, and it is not recommended to be the first-line treatment method. Currently, the most commonly used treatment for OSAHS is positive pressure ventilation, and the two most commonly used in clinical practice are AUTO-CPAP and CPAP, and the present study aims to summarise the differences in the effects of these two types of ventilators on the treatment of OSAHS patients.