Background: In Sub-Saharan Africa, pre-eclampsia remains a major health problem contributing to high rates of maternal mortality. Despite this condition having adverse effects on maternal and child health, its prevalence and associated risk factors are still significant, especially in developing countries including Ghana. This study aimed to assess the prevalence and demographic distributions associated with pre-eclampsia among pregnant women at the Ho Teaching Hospital. Methods: A facility-based retrospective study was conducted by reviewing available data or hospital records of pregnant mothers admitted to the labor and maternity wards from January 2018 to December 2020. All pregnant women who were diagnosed with pre-eclampsia within this period were included in the study. The data were collected using a structured checklist. Results: 5609 data on pregnant women from 2018 to 2020 were recorded. Out of the 5609 data recorded, 314 pre-eclampsia cases were recorded giving an overall prevalence of 5.6%. The yearly prevalence for 2018, 2019, and 2020 were 4.6%, 5.6%, and 6.6%, respectively. The most recorded pre-eclampsia cases were seen among women within the age group of 18 - 24 years. The data showed that 112 (35.7%) of the pregnant women who had pre-eclampsia were nulliparous. Pre-eclampsia-associated maternal and fetal complications were; preterm delivery 221 (70.4%), intrauterine fetal death 62 (19.7%), eclampsia 9 (2.9%), HELLP syndrome 5 (1.6%) and maternal death 17 (5.4%). Associated factors of pre-eclampsia were parity, level of education, and occupation (p ≤ 0.05). Conclusion: The findings of this study showed a rising trend in the incidence of pre-eclampsia over the years at the Ho Teaching Hospital. Parity, level of education, and occupation were found to be associated with developing pre-eclampsia.
References
[1]
Adu-Bonsaffoh, K., Ntumy, M.Y., Obed, S.A. and Seffah, J.D. (2017) Perinatal Outcomes of Hypertensive Disorders in Pregnancy at a Tertiary Hospital in Ghana. BMC Pregnancy and Childbirth, 17, Article No. 388. https://doi.org/10.1186/s12884-017-1575-2
[2]
Kooffreh, M., Ekott, M. and Ekpoudom, D. (2014) The Prevalence of Pre-Eclampsia among Pregnant Women in the University of Calabar Teaching Hospital, Calabar. Saudi Journal for Health Sciences, 3, 133-136. https://doi.org/10.4103/2278-0521.142317
[3]
Jane, R., Hans, M. and Ali, S. (2020) Maternal Near Miss and Mortality Attributable to Hypertensive Disorders in a Tertiary Hospital, Tanzania: A Cross-Sectional Study. BMC Pregnancy and Childbirth, 20, Article No. 301.
[4]
Otu-Nyarko, S., Asare, Q.G., Sackey, S. and Tagoe, E.A. (2015) Predictors of Pre-Eclampsia: A Hospital-Based Study in Accra, Ghana. Postgraduate Medical Journal of Ghana, 4, 66-72. https://doi.org/10.60014/pmjg.v4i2.150
[5]
Frank, I.O., Michael, J.M., Jenny, R. and Joseph, O. (2020) Prevalence and Risk Factors for Pre-Eclampsia/Eclampsia in Northern Tanzania.Journal of Public Health and Epidemiology, 12, 78-85. https://doi.org/10.5897/JPHE2019.1143
[6]
Dolea, C. and Abouzahr, C. (2003) Global Burden of Hypertensive Disorders of Pregnancy in the Year 2000. Global Burden of Diseases 2000 Working Paper. World Health Organization (WHO), Geneva.
[7]
Creanga, A.A., Syverson, C., Seed, K. and Callaghan, W.M. (2017) Pregnancy-Related Mortality in the United States, 2011-2013. Obstetrics and Gynecology, 130, 366-373. https://doi.org/10.1097/AOG.0000000000002114
[8]
Moussa, H.N., Arian, S.E. and Sibai, B.M. (2014) Management of Hypertensive Disorders in Pregnancy. Women’s Health, 10, 385-404. https://doi.org/10.2217/WHE.14.32
[9]
Klungsøyr, K., Morken, N.H., Irgens, L., Vollset, S.E. and Skjærven, R. (2012) Secular Trends in the Epidemiology of Pre-Eclampsia throughout 40 Years in Norway: Prevalence, Risk Factors, and Perinatal Survival. Pediatric and Perinatal Epidemiology, 26, 190-198. https://doi.org/10.1111/j.1365-3016.2012.01260.x
[10]
Schneider, S., Freerksen, N., Maul, H., Roehrig, S., Fischer, B. and Hoeft, B. (2011) Risk Groups and Maternal-Neonatal Complications Of Preeclampsia—Current Results from the National German Perinatal Quality Registry. Journal of Perinatal Medicine, 39, 257-263. https://doi.org/10.1515/jpm.2011.010
[11]
Ahenkorah, L. (2009) Metabolic Syndrome, Oxidative Stress and Putative Risk Factors amongst Ghanaian Women Presenting with Pregnancy-Induced Hypertension. http://ir.knust.edu.gh/handle/123456789/164
[12]
Obed, S. and Patience, A. (2006) Birth Weight and Ponderal Index in Pre-Eclampsia: A Comparative Study. Ghana Medical Journal, 40, 8-13. https://pubmed.ncbi.nlm.nih.gov/17299557/
[13]
Belay, A.S. and Wudad, T. (2019) Prevalence and Associated Factors of Pre-Eclampsia among Pregnant Women Attending Anti-Natal Care at Mettu Karl Referral Hospital, Ethiopia: A Cross-Sectional Study. Clinical Hypertension, 25, Article No. 14. https://doi.org/10.1186/s40885-019-0120-1
[14]
Guerrier, G., Oluyide, B., Keramarou, M. and Grais, R.F. (2013) Factors Associated with Severe Preeclampsia and Eclampsia in Jahun, Nigeria. International Journal of Women’s Health, 5, 509-513. https://doi.org/10.2147/IJWH.S47056
[15]
Fondjo, L.A., Boamah, V.E., Fierti, A., Gyesi, D. and Owiredu, E. (2019) Knowledge of Preeclampsia and Its Associated Factors among Pregnant Women : A Possible Link to Reduce Related Adverse Outcomes. BMC Pregnancy and Childbirth, 19, Article No. 456. https://doi.org/10.1186/s12884-019-2623-x
[16]
Logan, G.G., Njoroge, P.K., Nyabola, L.O. and Mweu, M.M. (2021) Determinants of Preeclampsia and Eclampsia among Women Delivering in County Hospitals in Nairobi, Kenya. F1000Research, 9, Article 192. https://doi.org/10.12688/f1000research.21684.1
[17]
Duley, L. (2009) The Global Impact of Pre-Eclampsia and Eclampsia. Seminars in Perinatology, 33, 130-137. https://doi.org/10.1053/j.semperi.2009.02.010
[18]
Jeyabalan, A. (2013) Epidemiology of Preeclampsia: Impact of Obesity. Nutrition Reviews, 71, S18–S25. https://doi.org/10.1111/nure.12055
[19]
Grum, T., Seifu, A., Abay, M., Angesom, T. and Tsegay, L. (2017) Determinants of pre-Eclampsia/Eclampsia among Women Attending Delivery Services in Selected Public Hospitals of Addis Ababa, Ethiopia: A Case-Control Study. BMC Pregnancy and Childbirth, 17, Article No. 307. https://doi.org/10.1186/s12884-017-1507-1
[20]
Kiondo, P., Wamuyu-Maina, G., Bimenya, G.S., Tumwesigye, N.M., Wandabwa, J. and Okong, P. (2012) Risk Factors for Pre-Eclampsia in Mulago Hospital, Kampala, Uganda. Tropical Medicine and International Health, 17, 480-487. https://doi.org/10.1111/j.1365-3156.2011.02926.x