白介素-6，C反应蛋白，纤维蛋白原对肛瘘、肛周脓肿辅助诊断的临床研究进展
Clinical Research Progress of Interleukin-6, C-Reactive Protein and Fibrinogen in the Auxiliary Diagnosis of Anal Fistula and Perianal Abscess

肛瘘和肛周脓肿是一种直肠和肛管炎症性疾病，肛周脓肿是化脓性感染的急性期，而肛瘘则是慢性期。以往一般根据患者的病史、临床症状、体格检查和实验室检查进行诊断，但是这些诊断方法的敏感性都不高，而CT、MRI也有检查的费用偏高、注射造影剂可能导致诊断过程变长以及在某些基层医疗机构中缺乏普及性等缺点，临床可对血浆的C反应蛋白(C-reactive protein, CRP)，白介素-6 (interleukin-6, IL-6)，纤维蛋白原(fibrinogen, FIB)进行检测，以期为临床提供新的诊断途径与方法，辅助诊断及鉴别肛瘘及肛周脓肿，从而提高治疗效率。
Anal fistula and perianal abscess is an inflammatory disease of rectum and anal canal. Perianal abscess is the acute stage of suppurative infection, while anal fistula is chronic. In the past, diag-nosis was generally made according to the patient’s medical history, clinical symptoms, physical examination and laboratory examination, but the sensitivity of these diagnostic methods was not high. CT and MRI also have some shortcomings, such as high cost of examination, injection of con-trast medium may lead to longer diagnostic process and lack of popularity in some primary health care institutions. Plasma C-reactive protein (CRP), interleukin-6 (IL-6) and fibrinogen (FIB) can be detected in clinic, in order to provide a new diagnostic approach and method for clinical diagnosis and differential diagnosis of anal fistula and perianal abscess, so as to improve the efficiency of treatment.