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胆囊胆固醇结石与人体微生物群相关性研究现状
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Abstract:
胆石症(Gallstone)是普通外科一种常见病、多发病，虽然大多数胆石症患者早期无明显临床症状，但是仍然有相当一部分患者后续会出现明显的症状，甚至出现不同程度的并发症。目前无论是早期发现的无症状胆石症，还是伴随有症状出现的胆石症，主流的治疗方案均为手术治疗。近些年，随着对胆囊胆固醇结石形成机制的深入研究，人体微生物群与胆固醇结石形成之间的存在的关系逐渐成为了胆石症研究的热点。本文意在通过查阅相关文献从不同人体菌落角度论述微生物群与胆囊结石发生的相关机制。
Gallstone is a common and frequently occurring disease in general surgery. Although most patients with gallstone have no obvious clinical symptoms at the early stage, a considerable number of pa-tients still have obvious symptoms and even complications of different degrees. At present, whether it is asymptomatic gallstone detected early or accompanied by symptoms, the mainstream treat-ment is surgical treatment. In recent years, with the in-depth study of the formation mechanism of gallbladder cholesterol stones, the relationship between human microbiota and cholesterol stone formation has gradually become a hot spot in the study of gallstone. This paper aims to discuss the mechanism of microbiota and gallstone occurrence from the perspective of different human colo-nies by referring to relevant literature.
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