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TYG指数在重症(急性)胰腺炎的预测价值中的研究进展
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Abstract:
近年来由于饮食模式及生活方式变化,急性胰腺炎(Acute pancreatitis, AP)的发病率一直在增加。作为临床常见急症之一,急性胰腺炎发病率呈逐年增高趋势,其中10%~20%的病人能很快发展成重症胰腺炎,而重症胰腺炎的预后,常常不容乐观,其给病人身体带来极大危害,对病人家庭造成严重的经济负担。所以,对AP严重程度进行早期、准确的评价就显得格外重要。已有急性生理及慢性健康状况评分II及改良Marshall评分均具有针对性,适用于全部危重病人,对胰腺炎的评价缺乏特异性;Ranson评分仅能对入院后48 h进行1次评价,时效性不强,不能做动态的评价。所以急需探讨一种敏感性好、特异性强的简便评价方法。
The incidence of acute pancreatitis has been increasing in recent years due to changing dietary patterns and lifestyles. As one of the common clinical emergencies, the incidence of acute pancrea-titis is increasing year by year, and 10%~20% of these patients can quickly develop into severe pancreatitis, as acute pancreatitis is characterized by insidious onset, rapid development and less severe cases. It brings great harm to patients’ health and serious economic burden to patients’ fam-ilies. Therefore, an early and accurate assessment of AP severity is particularly important. The acute physiological and chronic health status score II and the modified Marshall score are both spe-cific and applicable to all critically ill patients, but lack specificity for the evaluation of pancreatitis; the Ranson score can only be evaluated once 48 h after admission, which is not time-sensitive and cannot be evaluated dynamically. Therefore, there is an urgent need to explore a simple evaluation method with good sensitivity and high specificity.
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