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硬膜外脓肿的研究进展
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Abstract:
硬膜外脓肿是一种通过脊柱和硬膜外间隙的静脉发生在椎管内硬膜外的细菌感染。硬膜外脓肿患者早期会出现腰背疼痛、神经根性疼痛,以及发热、盗汗等全身症状,晚期可引起运动或感觉功能障碍,甚至出现瘫痪,严重影响患者的正常生活。早期诊断硬膜外脓肿是非常困难的,组织病理学是诊断金标准。目前,对于确诊硬膜外脓肿的首选保守治疗还是手术治疗、手术时机的选择以及预后已成为近年来的研究热点。本文对硬膜外脓肿的病理生理学、诊断治疗策略以及预后进行了全面综述。
Spinal epidural abscess (SEA) is a bacterial infection that occurs in the epidural canal through veins in the spinal column and epidural space. In the early stage, patients with epidural abscess will have lumbar and back pain, nerve root pain, fever, night sweats and other systemic symptoms. In the late stage, patients can cause motor or sensory dysfunction, or even paralysis, which seriously affects their normal life. Early diagnosis of epidural abscess is very difficult and histopathology is the gold standard. At present, the choice of conservative treatment or surgical treatment, the choice of sur-gical timing and prognosis for the diagnosis of epidural abscess has become a research hotspot in recent years. The pathophysiology, diagnosis and treatment strategies and prognosis of epidural abscess were reviewed in this paper.
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