精神分裂症药物和物理治疗方法研究进展
Advances in Drug and Physical Therapy for Schizophrenia

精神分裂症(schizophrenia)目前被认为是一组病因未明的重性精神障碍，具有认知、思维、情感、行为等多方面精神活动的显著异常。具有较高病发率，严重影响患者身心健康及生活质量，对国家经济发展及社会稳定有极大影响。目前药物仍是临床治疗该病首选方式，但存在依存性差，且不良反应较多等缺点，易加剧患者身心负担，新型研究药物正在努力克服这些缺点。近些年物理治疗逐渐在我国发展为治疗新型手段，效果良好，且可有效避免药物不良反应，而且对急性期患者效果较显著。本文将对药物治疗和物理治疗新进展分别论述，旨在对临床工作提供一些有效指导。
Schizophrenia is currently considered to be a group of severe mental disorders with unknown eti-ology, with significant abnormalities in cognitive, thinking, emotional, behavioral and other mental activities. It has high incidence rate, seriously affects patients’ physical and mental health and quality of life, and greatly affects national economic development and social stability. At present, drugs are still the first choice for clinical treatment of this disease, but they have the disadvantages of poor dependence, and more adverse reactions, which easily aggravate the physical and mental burden of patients. New research drugs are trying to overcome these shortcomings. In recent years, physical therapy has gradually developed into a new treatment method in China, with good results. Besides, it can effectively avoid adverse drug reactions, and has a significant effect on patients in the acute phase. In this article, we discuss the new advances in drug therapy and physical therapy, respectively, in order to provide some effective guidance for clinical work.