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甘油三酯葡萄糖乘积指数与胰岛素抵抗在肾脏疾病中的研究进展
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Abstract:
近年来，甘油三酯葡萄糖乘积指数(TyG指数)已经成为研究热点，是评估胰岛素抵抗(IR)的新型指标。有研究发现该指数是评估蛋白尿、慢性肾脏病(CKD)及心血管疾病(CVD)等的有效生物标志物。同时，目前已被证明与2型糖尿病、代谢综合征、血管性认知功能障碍、多囊卵巢综合征、恶性肿瘤等多种疾病风险相关。本文主要针对TyG指数在肾脏疾病中的研究进展做一综述，以期为肾脏疾病进展、并发症防治和预后的预测提供新依据，为临床早期诊断和干预提供新思路。
In recent years, the Triglyceride-Glucose Index (TyG index) has become a research hotspot and is a new index for evaluating insulin resistance (IR). Studies have found that the index is an effective biomarker for evaluating proteinuria, chronic kidney disease (CKD) and cardiovascular disease (CVD). At the same time, it has been proven to be associated with the risk of various diseases, such as type 2 diabetes, metabolic syndrome, vascular cognitive impairment, polycystic ovary syndrome and malignant tumors. This article mainly reviews the research progress of TyG index in renal disease, in order to provide a new basis for the prediction of renal disease progression, complication prevention and prognosis, and to provide new ideas for early clinical diagnosis and intervention.
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