There is a long ritual of acquired immunity using physical exercise, a balanced diet, and pharmaceutical medication to generate immunity against a particular disease insight into the human body. This paper has extensively reviewed the impact of exercise, daily life practice, food selection, and several other issues to improve the immune system that combat infection. Studying the effect of exercise in varying degrees on the immunity system of humans is well developed and exhibit in this study. It investigates the prevention of pandemics due to herd immunity and finds the perfect amount of exercise to boost immunity to its maximum. Besides the life practice, it is also explored that vaccination can improve and optimize herd immunity.
References
[1]
DeRoo, S.S., et al. (2020) Planning for a COVID-19 Vaccination Program. JAMA, 323, 2458-2459. https://doi.org/10.1001/jama.2020.8711
[2]
WHO (2020) Coronavirus (COVID-19) Dashboard. https://covid19.who.int
[3]
(2021) Global COVID-19 Death Toll More than Double the Estimates: Study. https://www.aljazeera.com/news/2021/5/7/global-covid-19-death-toll-more-than-double-the-estimates-study
[4]
How COVID Vaccines Work against the Delta Variant, 16 June 2021. https://www.aljazeera.com/news/2021/6/16/how-covid-vaccines-work-against-delta-variant
[5]
Chowdhury, M.A., et al. (2020) Immune Response in COVID-19: A Review. Journal of Infection and Public Health, 13, 1619-1629. https://doi.org/10.1016/j.jiph.2020.07.001
[6]
Makhlouf, A.M., El-Shennawy, L. and Elkaranshawy, H.A. (2020) Mathematical Modelling for the Role of CD4+ T Cells in Tumor-Immune Interactions. Computational and Mathematical Methods in Medicine, 2020, Article ID: 7187602. https://doi.org/10.1155/2020/7187602
[7]
Sitlinger, A., Brander, D.M. and Bartlett, D.B. (2020) Impact of Exercise on the Immune System and Outcomes in Hematologic Malignancies. Blood Advances, 4, 1801-1811. https://doi.org/10.1182/bloodadvances.2019001317
[8]
Chowdhury, M. (2021, April 11) Recommendation for the Gap between Two Doses of COVID-19 Vaccine. The Daily Star.
[9]
Ellis, R. (2021) Pfizer, Moderna Say Booster Shots Probably Needed. https://www.webmd.com
[10]
McCallum, K. (2020) What Happens If You Miss Your 2nd COVID-19 Shot? https://www.health.com/condition/infectious-diseases/coronavirus
[11]
Druss, B.G. (2020) Addressing the COVID-19 Pandemic in Populations with Serious Mental Illness. JAMA Psychiatry, 77, 891-892. https://doi.org/10.1001/jamapsychiatry.2020.0894
[12]
(2020) Focusing on Vulnerable Populations during COVID-19. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363379/pdf/acm-publish-ahead-of-print-10.1097.acm.0000000000003571.pdf
[13]
(2020) India under COVID-19 Lockdown. The Lancet, 395, 1315. https://www.thelancet.com https://doi.org/10.1016/S0140-6736(20)30938-7
[14]
Kamrujjaman, M., et al. (2021) SARS-CoV-2 and Rohingya Refugee Camp, Bangladesh: Uncertainty and How the Government Took over the Situation. Biology (Basel), 10, 124. https://doi.org/10.3390/biology10020124
[15]
Hassan, M., Mahmud, M., Nipa, K. and Kamrujjaman, M. (2021) Mathematical Modeling and COVID-19 Forecast in Texas, USA: A Prediction Model Analysis and the Probability of Disease Outbreak. Disaster Medicine and Public Health Preparedness, 1-12. https://doi.org/10.1017/dmp.2021.151
[16]
Mahmud, M.S., Kamrujjaman, M., Jubyrea, J., Islam, M.S. and Islam, M.S. (2020) Quarantine vs. Social Consciousness: A Prediction to Control COVID-19 Infection. Journal of Applied Life Sciences International, 23, 20-27. https://doi.org/10.9734/jalsi/2020/v23i330150
[17]
Kamrujjaman, M., Mahmud, M.S. and Islam, M.S. (2020) Coronavirus Outbreak and the Mathematical Growth Map of COVID-19. Annual Research & Review in Biology, 35, 72-78. https://doi.org/10.9734/arrb/2020/v35i130182
[18]
Islam, M.S., et al. (2020) Effect of Lockdown and Isolation to Suppress the COVID-19 in Bangladesh: An Epidemic Compartments Model. Journal of Applied Mathematics and Computation, 4, 83-93. https://doi.org/10.20944/preprints202004.0193.v2
[19]
Sallis, R., et al. (2021) Physical Inactivity Is Associated with a Higher Risk for Severe COVID-19 Outcomes: A Study in 48 440 Adult Patients. British Journal of Sports Medicine, 1-8. https://doi.org/10.1136/bjsports-2021-104080
[20]
Antunes, R. (2021) Physical Activity and Mental Health in Covid-19 Times: An Editorial. Sleep Medicine, 77, 295-296. https://doi.org/10.1016/j.sleep.2020.10.007
[21]
Azar, A.M. (2018) Physical Activity Guidelines for Americans. U.S. Department of Health and Human Services, Washington DC.
[22]
Booth, F.W., Roberts, C.K. and Laye, M.J. (2012) Lack of Exercise Is a Major Cause of Chronic Diseases. Comprehensive Physiology, 2, 1143-1211. https://doi.org/10.1002/cphy.c110025
[23]
Shahidi, S.H., Williams, J.S. and Hassani, F. (2020) Physical Activity during COVID-19 Quarantine. Acta Paediatrica, 109, 2147-2148. https://doi.org/10.1111/apa.15420
[24]
Kaur, H., et al. (2020) Physical Fitness and Exercise during the COVID-19 Pandemic: A Qualitative Enquiry. Frontiers in Psychology, 11, Article ID: 590172. https://doi.org/10.3389/fpsyg.2020.590172
[25]
WHO (2020, November 26) Physical Activity. https://www.who.int/news-room/fact-sheets/detail/physical-activity
[26]
GOV.UK (2019) Physical Activity: Applying All Our Health.
[27]
Sutherland, A. (2020) The One Organ Responsible for All Cases of High Blood Pressure and the Simple Exercises That Lower It. https://avasuther.quora.com/The-one-organ-responsible-for-ALL-cases-of-high-blood-pressure-and-the-simple-exercises-that-lower-it-1
[28]
Brolinson, G.P. and Elliott, D. (2007) Exercise and the Immune System. Clinics in Sports Medicine, 26, 311-319. https://doi.org/10.1016/j.csm.2007.04.011
[29]
Simpson, R.J., Campbell, J.P., Gleeson, M., Krüger, K., Nieman, D.C., Pyne, D.B., Turner, J.E. and Walsh, N.P. (2020) Can Exercise Affect Immune Function to Increase Susceptibility to Infection? Exercise Immunology Review, 26, 8-22.
[30]
Ahmed, K.R., Uddin, R., Kolbe-Alexander, T.L. and Khan, A. (2021) The Effectiveness of Physical Activity Interventions in Asian Children and Adolescents: A Systematic Review. Public Health, 194, 48-59. https://doi.org/10.1016/j.puhe.2021.02.011
[31]
Nilsson, M., Kelly, P., Smith, J., Raine, L. and Biddle, S. (2020) Physical Activity for Cognitive and Mental Health in Youth: A Systematic Review of Mechanisms. Pediatrics, 138, e20161642.
[32]
Li, A.W. and Goldsmith, C.-A.W. (2012) The Effects of Yoga on Anxiety and Stress. Alternative Medicine Review, 17, 21-35.
[33]
Lubans, D., Richards, J., Hillman, C., et al. (2016) Physical Activity for Cognitive and Mental Health in Youth: A Systematic Review of Mechanisms. Pediatrics, 138, e20161642. https://doi.org/10.1542/peds.2016-1642
[34]
Pascoe, M., et al. (2020) Physical Activity and Exercise in Youth Mental Health Promotion: A Scoping Review. BMJ Open Sport & Exercise Medicine, 6, e000677. https://doi.org/10.1136/bmjsem-2019-000677
[35]
Deslandes, A., et al. (2009) Exercise and Mental Health: Many Reasons to Move. Neuropsychobiology, 59, 191-198. https://doi.org/10.1159/000223730
[36]
Falkenberg, R.I., Eising, C. and Peters, M.L. (2018) Yoga and Immune System Functioning: A Systematic Review of Randomized Controlled Trials. Journal of Behavioral Medicine, 41, 467-482. https://doi.org/10.1007/s10865-018-9914-y
[37]
Pruett, S.B. (2003) Stress and the Immune System. Pathophysiology, 9, 133-153. https://doi.org/10.1016/S0928-4680(03)00003-8
[38]
Sutherland, A. (2020) Reducing Blood Pressure Naturally Book—The Most Complete Guide to Cure High Blood Pressure without Medications.
[39]
Swanson, A. (2019) Science of Yoga: Understand the Anatomy and Physiology to Perfect Your Practice. https://www.yogajournal.com/meditation/science-of-meditation/science-behind-being-present
[40]
Stewart, G. (2004) The Immune System. Chelsea House Publishers, New York.
[41]
Sompayrac, L. (2019) How the Immune System Works. Sixth Edition, John Wiley & Sons, Ltd., Hoboken.
[42]
Clemente-Suárez, V.J., et al. (2020) Dynamics of Population Immunity Due to the Herd Effect in the COVID-19 Pandemic. Vaccines, 8, 236. https://doi.org/10.3390/vaccines8020236
[43]
Hossain, M.J. (2020) Is Bangladesh Moving toward Herd Immunity? Current COVID-19 Perspective. Bangladesh Journal of Infectious Diseases, 7, S63-S66. https://doi.org/10.3329/bjid.v7i00.50166
[44]
Fine, P., Eames, K. and Heymann, D.L. (2011) Herd Immunity: A Rough Guide. Clinical Infectious Diseases, 52, 911-916. https://doi.org/10.1093/cid/cir007
[45]
Desai, A.N. and Majumder, M.S. (2020) What Is Herd Immunity? JAMA, 324, 2113. https://jamanetwork.com https://doi.org/10.1001/jama.2020.20895
[46]
Omer, S.B., Yildirim, I. and Forman, H.P. (2020) Herd Immunity and Implications for SARS-CoV-2 Control. JAMA, 324, 2095-2096. https://doi.org/10.1001/jama.2020.20892
Metcalf, C.J.E., Ferrari, M., Graham, A.L. and Grenfell, B.T. (2015) Understanding Herd Immunity. Trends in Immunology, 36, 753-755. https://www.thelancet.com https://doi.org/10.1016/j.it.2015.10.004
[49]
Edenfield, T.M. and Saeed, S. (2012) An Update on Mindfulness Meditation as a Self-Help Treatment for Anxiety and Depression. Psychology Research and Behavior Management, 5, 131-141. https://doi.org/10.2147/PRBM.S34937
[50]
Anderson, R.M., Vegvari, C., Truscott, J. and Collyer, B.S. (2020) Challenges in Creating Herd Immunity to SARS-CoV-2 Infection by Mass Vaccination. The Lancet, 396, 1614-1616. https://doi.org/10.1016/S0140-6736(20)32318-7
[51]
Venkatasen, M., et al. (2020) Forecasting of the SARS-CoV-2 Epidemic in India Using SIR Model, Fatten Curve and Herd Immunity. Journal of Ambient Intelligence and Humanized Computing, 1-9. https://doi.org/10.1007/s12652-020-02641-4
[52]
Shapiro, D., et al. (2007) Yoga as a Complementary Treatment of Depression: Effects of Traits and Moods on Treatment Outcome. Advance Access Publication, 4, 493-502. https://doi.org/10.1093/ecam/nel114
[53]
Smith, J.A., Greer, T., Sheets, T. and Watson, S. (2011) Is There More to Yoga than Exercise? Alternative Therapies, 17, 22-29.
[54]
Scott, E. (2020) The Benefits of Yoga for Stress Management. https://www.verywellmind.com/the-benefits-of-yoga-for-stress-management-3145205
[55]
Andrew Weil, M.D. (2020) Immunity-Boosting Yoga for Children: 7 Asanas to Build Stronger Immune System. https://www.india.com/health
[56]
Doria-Rose, N. and Suthar, M.S. (2021) Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19. The New England Journal of Medicine, 384, 2259-2261. http://nejm.org https://doi.org/10.1056/NEJMc2103916
[57]
Santino, T.A., et al. (2020) Breathing Exercises for Adults with Asthma. Cochrane Database of Systematic Reviews, No. 3, CD001277. https://doi.org/10.1002/14651858.CD001277.pub4
[58]
Saeed, S.Y.A., Antonacci, D.J. and Bloch, R.M. (2010) Exercise, Yoga, and Meditation for Depressive and Anxiety Disorders. American Family Physician, 81, 981-986.
[59]
Li, J.G., et al. (2021) Yoga for Secondary Prevention of Coronary Heart Disease: A Systematic Review and Meta-Analysis. Complementary Therapies in Medicine, 57, Article ID: 102643. https://doi.org/10.1016/j.ctim.2020.102643
[60]
Kiecolt-Glaser, J.K., et al. (2010) Stress, Inflammation, and Yoga Practice. Psychosomatic Medicine, 72, 113. https://doi.org/10.1097/PSY.0b013e3181cb9377
[61]
Sharma, K., Anand, A. and Kumar, R. (2020) The Role of Yoga in Working from Home during the COVID-19 Global Lockdown. Work, 66, 731-737. https://doi.org/10.3233/WOR-203219
[62]
Sinclair, D., Purves-Tyson, T.D., Allen, K.M. and Weickert, C.S. (2014) Impacts of Stress and Sex Hormones on Dopamine Neurotransmission in the Adolescent Brain. Psychopharmacology, 231, 1581-1599. https://doi.org/10.1007/s00213-013-3415-z
[63]
Glaser, R. and Kiecolt-Glaser, J. (2014) Stress Damages Immune System and Health. Psychopharmacology, 231, 1581-1599.
[64]
Marketon, J.I.W. and Glaser, R. (2008) Stress Hormones and Immune Function. Cellular Immunology, 252, 16-26. https://doi.org/10.1016/j.cellimm.2007.09.006
[65]
Raupach, T., Bahr, F., Herrmann, P., Luethje, L., Heusser, K., Hasenfuß, G., Bernardi, L. and Andreas, S. (2008) Slow Breathing Reduces Sympathoexcitation in COPD. European Respiratory Journal, 32, 387-392. https://doi.org/10.1183/09031936.00109607
[66]
Russo, M.A., Santarelli, D.M. and O’Rourke, D. (2017) The Physiological Effects of Slow Breathing in the Healthy Human. Breathe, 13, 298-309. https://doi.org/10.1183/20734735.009817
[67]
Perciavalle, V., et al. (2016) The Role of Deep Breathing on Stress. Neurological Sciences, 38, 451-458.
[68]
Andrew Weil, M.D. (2020) Three Breathing Exercises. http://www.drweil.com/drw/u/ART00521/three-breathing-exercises.html
[69]
Bhagat, V., Haque, M. and Jaalam, K. (2017) Breathing Exercise—A Commanding Tool for Self-Help Management during Panic Attacks. Research Journal of Pharmacy and Technology, 10, 4471-4473. https://doi.org/10.5958/0974-360X.2017.00825.3
[70]
Joseph, C.N., et al. (2005) Slow Breathing Improves Arterial Baroreflex Sensitivity and Decreases Blood Pressure in Essential Hypertension. Hypertension, 46, 714-718. https://doi.org/10.1161/01.HYP.0000179581.68566.7d
[71]
Rucklidge, J.J. and Schofield, G. (2020) Coronavirus and Underlying Medical Conditions: Improving Immunity through Lifestyle Choice. The Conversation.
[72]
Bird, S.R. and Hawley, J.A. (2016) Update on the Effects of Physical Activity on Insulin Sensitivity in Humans. BMJ Open Sport & Exercise Medicine, 2, e000143. https://doi.org/10.1136/bmjsem-2016-000143
[73]
Club Industry (2021) Less Physically Active People Have Higher Risk of Severe COVID-19 Outcomes, per Study. https://www.clubindustry.com/fitness-studies/less-physically-active-people-have-higher-risk-severe-covid-19-outcomes-per-study
[74]
Berman, R. (2021) Exercise and Mental Health during the COVID-19 Pandemic. https://www.medicalnewstoday.com/articles/exercise-and-mental-health-during-covid-19-study-explores-link-trends
[75]
Marashi, M.Y., Nicholson, E., Ogrodnik, M., Fenesi, B. and Heisz, J. (2021) A Men and Barrier to Health Paradox: Mental Health Was Both a Motivator Physical Activity during the COVID-19 Pandemic. PLoS ONE, 16, e0239244. https://doi.org/10.1371/journal.pone.0239244
[76]
Luzi, L. and Radaelli, M.G. (2020) Influenza and Obesity: Its Odd Relationship and the Lessons for COVID-19 Pandemic. Acta Diabetologica, 57, 759-764. https://doi.org/10.1007/s00592-020-01522-8
[77]
Morrison, C. (2008) Interaction between Exercise and Leptin in the Treatment of Obesity. Diabetes, 57, 534-535. https://doi.org/10.2337/db08-0007
[78]
Vancampfort, D., et al. (2017) Sedentary Behavior and Physical Activity Levels in People with Schizophrenia, Bipolar Disorder and Major Depressive Disorder: A Global Systematic Review and Meta-Analysis. World Psychiatry, 16, 308-315. https://doi.org/10.1002/wps.20458
[79]
SaVanna, S. (2021) 9 Ways to Boost Your Body’s Natural Defense. https://www.mdseniorresource.org/2020/06/02/9-ways-to-boost-your-bodys-natural-defenses
[80]
Chastin, S. (2020) Exercise Boosts Immunity and Makes Vaccines More Effective—New Study. https://www.gavi.org/vaccineswork/exercise-boosts-immunity-and-makes-vaccines-more-effective-new-study
[81]
WHO (2020) Physical Activity: Staying Active.
[82]
Laddu, D.R., Lavie, C.J., Phillips, S.A. and Arena, R. (2020) Physical Activity for Immunity Protection: Inoculating Populations with Healthy Living Medicine in Preparation for the Next Pandemic. Progress in Cardiovascular Diseases, 64, 102-104. https://doi.org/10.1016/j.pcad.2020.04.006
[83]
Pedersen, B.K. and Hoffman-Goetz, L. (2000) Exercise, and the Immune System: Regulation Integration and Adaption. Physiological Reviews, 80, 1055-1081. https://doi.org/10.1152/physrev.2000.80.3.1055
[84]
Leandro, C.G., Castro, R.M., Nascimento, E., Pithon-Curi, T.C. and Curi, R. (2007) Adaptative Mechanisms of the Immune System in Response to Physical Training. Revista Brasileira de Medicina do Esporte, 13, 343-348. https://doi.org/10.1590/S1517-86922007000500012
[85]
Simpson, R.J. and Katsanis, E. (2020) The Immunological Case for Staying Active during the COVID-19 Pandemic. Brain, Behavior, and Immunity, 87, 6-7. https://doi.org/10.1016/j.bbi.2020.04.041
[86]
Walsh, N.P., Gleeson, M., Pyne, D.B., et al. (2011) Position Statement Part Two: Maintaining Immune Health. Exercise Immunology Review, 17, 64-103.
[87]
Haydon, A.M.M., Maclinnis, R.J., English, D.R. and Giles, G.G. (2005) The Effect of Physical Activity and Body Size on Survival after Diagnosis with Colorectal Cancer. Gut, 55, 62-67.
[88]
Lee, I.M. (2003) Physical Activity and Cancer Prevention—Data from Epidemiologic Studies. Medicine & Science in Sports & Exercise, 35, 1823-1827. https://doi.org/10.1249/01.MSS.0000093620.27893.23
[89]
Nurmasitoh, T. (2015) Physical Activities, Exercises, and Their Effects to the Immune System. Jurnal kedokteran dan kesehatan Indonesia, 7, 52-58. https://doi.org/10.20885/JKKI.Vol7.Iss2.art4
[90]
da Silveira, M.P., da Silva Fagundes, K.K., Bizuti, M.R., Starck, é., Rossi, R.C., de Resende, E. and Silva, D.T. (2021) Physical Exercise as a Tool to Help the Immune System against COVID-19: An Integrative Review of the Current Literature. Clinical and Experimental Medicine, 21, 15-28. https://doi.org/10.1007/s10238-020-00650-3
[91]
Schijns, V.E. (2001) Activation and Programming of Adaptive Immune Responses by Vaccine Adjuvants.
[92]
Goldsby, R., Kindt, T.J., Osborne, B.A. and Kuby, J. (2003) Chapter 2: Cells and Organs of the Immune System. In: Freeman, W.H., Ed., Immunology, 5th Edition, New York, 24-56.
[93]
(2021) 5 Ways to Boost Your Immunity without Any Supplements. https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/5-ways-to-boost-your-immunity-without-anysupplements/photostory/82769589.cms
[94]
Calder, P.C. and Jackson, A.A. (2000) Undernutrition, Infection and Immune Function. Nutrition Research Reviews, 13, 3-29. https://doi.org/10.1079/095442200108728981
[95]
Sekhon, H.K. and Kaur, G. (2014) Sex Hormone and Immune Dimorphism. The Scientific World Journal, 2014, Article ID: 159150. https://doi.org/10.1155/2014/159150
[96]
American Cancer Society (2019) Immunotherapy, Cytokines and Their Side Effects.
[97]
Ahmed, S.A. and Penhale, W.J. (1982) The Influence of Testosterone on the Development of Autoimmune Thyroiditis in Thymectomized and Irradiated Rats. Clinical & Experimental Immunology, 48, 367-374.
[98]
Mandal, A. (2019) Hormones and Where Do Hormones Release from. News Medical: Life Sciences, November.
[99]
Mandal, A. (2019) Effects of Hormone. News Medical: Life Sciences, November.
[100]
Breuning, L.G. (2012) Meet Your Happy Chemicals: Dopamine, Endorphin, Oxytocin. Serotonin-Inner Mammal Institute.
[101]
Mandal, A. (2019) What Are Hormones? https://www.news-medical.net/health/What-are-Hormones.aspx
[102]
Jacob, C., Litorco, J. and Lee, L. (2004) Immunity through Swarms: Agent-Based Simulations of the Human Immune System. International Conference on Artificial Immune Systems (ICARIS), Catania, 13-16 September 2004, 400-412. https://doi.org/10.1007/978-3-540-30220-9_32
[103]
Clark, W.R. (2007) In Defense of Self How the Immune System Really Works. Oxford University Press, Oxford.
[104]
Stocchi, V., De Feo, P. and Hood, D.A. (2007) Role of Physical Exercise in Preventing Disease and Improving the Quality of Life, Springer-Verlag Mailand.
[105]
Simpson, R.J., Campbell, J.P., Gleeson, M., Kruger, K., Nieman, D.C., Pyne, D.B., Turner, J.E. and Walsh, N.P. (2020) Can Exercise Affect Immune Function to Increase Susceptibility to Infection? Exercise Immunology Review, 26, 8-22.
[106]
da Silveira, M.P., et al. (2021) Physical Exercise as a Tool to Help the Immune System against COVID-19: An Integrative Review of the Current Literature. Clinical and Experimental Medicine, 21, 15-28. https://doi.org/10.1007/s10238-020-00650-3
Berman, R. (2020) Exercise and Mental Health during the COVID-19 Pandemic. https://www.medicalnewstoday.com/articles/exercise-and-mental-health-during-covid-19-study-explores-link-trends
[110]
Archer, T. and Garcia, D. (2015) Exercise and Dietary Restriction for Promotion of Neurohealth Benefits. Health, 7, 136-152. https://doi.org/10.4236/health.2015.71016
[111]
Nagendra, H.R. (2020) Yoga for COVID-19. International Journal of Yoga, 13, 87-88. https://doi.org/10.4103/ijoy.IJOY_27_20
[112]
Russo, M.A., Santarelli, D.M. and O’Rourke, D. (2017) The Physiological Effects of Slow Breathing in the Healthy Human. Breathe, 13, 298-309. https://doi.org/10.1183/20734735.009817
[113]
Brennan, D. (2021) What Foods Are Highest in Vitamin D? https://www.medicinenet.com/what_foods_are_highest_in_vitamin_d/article.htm
[114]
Lee, G.Y. and Han, S.N. (2018) The Role of Vitamin E in Immunity. Nutrients, 10, 1614. https://doi.org/10.3390/nu10111614
[115]
Kamrujjaman, M., Mahmud, M.S. and Islam, M.S. (2021) Dynamics of a Diffusive Vaccination Model with Therapeutic Impact and Non-Linear Incidence in Epidemiology. Journal of Biological Dynamics, 15, S105-S133. https://doi.org/10.1080/17513758.2020.1849831
[116]
Mahmud, M.S., Kamrujjaman, M. and Islam, M.S. (2019) A Spatially Dependent Vaccination Model with Therapeutic Impact and Non-Linear Incidence. In: Mishra, S.R., Dhamala, T.N., Makinde, O.D., Eds., Recent Trends in Applied Mathematics. Lecture Notes in Mechanical Engineering, Springer, Singapore. https://doi.org/10.1007/978-981-15-9817-3_22
[117]
Hansen, M.D. (2010) How Exercise Benefits the Immune System.
[118]
(2021, February 3) Everything You Need to Know about Herd Immunity and the Dangers Associated with It. Times of India.
[119]
(2021, January 23) Health Essentials: The Short Answer from an Immunity and Pulmonary Medicine Physician.
[120]
(2021) Triple mutation Covid variant in India? https://timesofindia.indiatimes.com/india/triple-mutation-covid-variant-in-india-heres-what-we-know-so-far/articleshow/82183386.cms
[121]
Cherian, S., et al. (2021) Convergent Evolution of SARS-CoV-2 Spike Mutations, L452R, E484Q and P681R, in the Second Wave of COVID-19 in Maharashtra, India. NIC Team. https://doi.org/10.1101/2021.04.22.440932
[122]
Hoffmann, M., et al. (2021) SARS-CoV-2 Variant B.1.617 Is Resistant to Bamlanivimab and Evades Antibodies Induced by Infection and Vaccination. https://doi.org/10.1101/2021.05.04.442663
[123]
Yadav, P.D., et al. (2021) SARS CoV-2 Variant B.1.617.1 Is Highly Pathogenic in Hamsters than B.1 Variant. https://doi.org/10.1101/2021.05.05.442760
[124]
Yadav, P., et al. (2021) Neutralization of Variant under Investigation B 1.617 with Sera of BBV152 Vaccines. https://doi.org/10.1101/2021.04.23.441101
