清脂茶的减肥降脂作用与有效成分分析
Effects of Qingzhi Tea on Reducing Weight and Analysis of Its Effective Components

DOI: 10.12677/HJFNS.2021.101001, PP. 1-9

Keywords: 中药代茶饮，高脂模型，减肥降脂，有效成分分析
Chinese Herbal Tea, High-Fat Model, Weight Loss, Effective Components Analysis

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Abstract:

目的：研究一种中药代茶饮清脂茶的减肥降脂功效及其发挥功效的物质基础。方法：将30只ICR小鼠分成空白组、模型组和清脂组(380 mg/kg)，小鼠采用饲喂高脂饲料法建立肥胖症小鼠模型，建模成功后，给予清脂组小鼠清脂茶30 d。探究清脂茶对小鼠体重、肥胖指数、脂肪含量、脂肪指数、总甘油三酯、总胆固醇、脂肪组织等产生的影响。此外，利用HPLC-Q-TOF-MS分析和确定清脂茶中减脂的有效成分。结果：与模型组相比，清脂组小鼠的体重、肥胖指数、脂肪含量、脂肪指数、总甘油三酯和总胆固醇水平均下降，其脂肪组织的病理状态也明显改善。结论：清脂茶可以有效改善高脂饮食小鼠的肥胖状态，实现调控血脂、减少脂肪积累、从而实现控制体重的目的。
Objective: To study the effects of Qingzhi tea on reducing weight and its material basis. Methods: 30 ICR mice were divided into blank group, model group and Qingzhi group (380 mg/kg). The obesity mice model was established by feeding high-fat diet to explore the effects of Qingzhi tea on body weight, obesity index, fat content, fat index, fat tissue, blood and liver of mice. In addition, HPLC-Q-TOF-MS was used to analyze and determine the effective weight-reducing components in Qingzhi tea. Results: Compared with the model group, the body weight, fat index, fat content, fat index, total triglyceride and total cholesterol levels of the Qingzhi group decreased, and the state of fat tissue also improved significantly. Conclusion: Qingzhi tea can effectively improve the obesity status of high-fat diet mice, achieve the goal of regulating blood lipids, reduce fat accumulation, and thus control body weight.

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