Combined modality treatment in mesothelioma: a systemic literature review with treatment recommendations

It was first suggested in 1980 that selected patients with malignant pleural mesothelioma (MPM) are to be treated with a combination of different therapeutic modalities, usually surgery, chemotherapy (CT) and radiotherapy (RT), in order to achieve locoregional control and to improve overall outcome (1). Other types of neoplasms that are treated in this manner include lung (2), esophageal (3) and colorectal cancer (4)