Morphological alterations induced by the exposure to TiO2 nanoparticles in primary cortical neuron cultures and in the brain of rats

DOI: 10.1016/j.toxrep.2018.08.006

Keywords: NPs, nanoparticles, BBB, blood-brain barrier, ROS, reactive oxygen species, MDA, malondialdehyde, NO, nitric oxide, IL-1β, interleukin-1β, TNF-α, tumor necrosis factor-α, IL-10, interleukin-10, IP, intraperitoneal, DLS, dynamic light scattering, HBSS, Hank's balanced salt solution, FBS, fetal bovine serum, BrdU, 5-Bromo-2′-deoxyuridine, SEM, standard error of the mean, MAP2, microtubule-associated protein 2, GFAP, glial fibrillary acidic protein, 4-HNE, 4-hydroxynonenal, NMDA, N-methyl-D-aspartate, NOS, nitric oxide synthase, ATP, adenosine triphosphate, CNS, central nervous system Nanoparticles, Brain, Cell culture, Oxidative stress, Proliferation

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