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-  2018 

Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells

DOI: 10.1038/s41389-018-0075-1

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Abstract:

SK-BR3 cells treated with the indicated concentrations of Gefitinib over a time period of 24?h, 48?h, or 72?h (a). BT474 cells treated with the indicated concentrations of Gefitinib over a time period of 24?h, 48?h, or 72?h (b). SK-BR3 cells treated with the indicated concentrations of Lapatinib over a time period of 24?h, 48, or 72?h (c). BT474 cells treated with the indicated concentrations of Lapatinib over a time period of 24?h, 48?h, or 72?h (d). (N?=?3

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