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-  2017 

Integrative research agenda for diagnosis in sepsis

DOI: 10.21037/atm.2017.06.57

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Abstract:

Intensive care medicine deals with the most critically and time-sensitive patients in the hospital. Each patient requires individualised point-of-care (POC) management and continuous care. In recent years high rates of sepsis and septic shock in intensive care unit (ICU) medicine have become omni-present. Sepsis is a severe systemic inflammatory response in which the host response to infection causes organ dysfunction and raises mortality risk. The time-sensitive nature of sepsis is exacerbated by the variable nature of presentation and a lack of medical consensus on diagnostic parameters. Correct diagnosis and treatment must take into account variables such as the infectious agent, the primary site of infection, patient comorbidities as well as the individual host response (1)

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