全部 标题 作者 关键词 摘要
DOI: 10.3971/j.issn.1000-8578.2015.10.004
Keywords: A Meta-analysis,Effect of Rap2a on Invasion and Metastasis of Lung Cancer Cells and Its Related Mechanism,Immune Killing Effect of Silencing TIPE2 Expression on T Lymphocytes Against Lung Adenocarcinoma Cells LA795,NSCLC的疫苗治疗研究进展,Experiment of Different Administration Sequences of Apatinib and Paclitaxel on Lung Cancer,Expressions of MACC1 and c-Met Proteins in Lung Adenocarcinoma and Their Correlation with Postoperative Recurrence,Cryptotanshinone Promotes Apoptosis of A549 Cells via Inhibiting Cap-dependent mRNA Translation,Clinical Investigation on Qingfei Mixture Combined with Chemotherapy on Middle and Advanced Non-small Cell Lung Cancer,Effect of Vascular Endothelial Cadherin on Invasion and Metastasis of Non-small Cell Lung Cancer Cells and Related Mechanism
Full-Text Cite this paper Add to My Lib
摘要 目的 探讨扁柏醇（Hinokitiol）联合氯喹对人肺腺癌（H1975）细胞凋亡的影响。方法 选用人肺腺癌H1975细胞系，应用MTT法检测扁柏醇和（或）氯喹对H1975细胞活性的影响，Westernblot法检测扁柏醇和（或）氯喹对H1975细胞凋亡通路相关蛋白（Cleaved PARP、Cleaved Caspase-3、Bax）表达水平的影响。结果 0、2.5、5、10 μmol/L扁柏醇作用H1975细胞24 h后，呈剂量依赖性地抑制H1975细胞增殖，H1975细胞凋亡相关蛋白（Cleaved PARP、Cleaved Caspase-3、Bax）表达水平升高。当氯喹和扁柏醇联合应用时，与单用扁柏醇相比，显著降低H1975细胞存活率，并提高H1975细胞凋亡率，凋亡相关蛋白Cleaved PARP、Cleaved Caspase-3表达水平显著增加。结论 氯喹增加扁柏醇诱导人肺腺癌H1975细胞凋亡
Full-Text
Contact Us
service@oalib.com
QQ:3279437679
WhatsApp +8615387084133
