儿童系统性红斑狼疮合并血栓性血小板减少性紫癜1例
Child-Onset Systemic Lupus Erythematosus Associated with Thrombotic Thrombocytopenic Purpura: A Case Report

系统性红斑狼疮(Systemic Lupus Erythematosus, SLE)是一种较为常见的自身免疫性疾病，往往易合并狼疮性肾炎。儿童系统性红斑狼疮(Child-Onset Systemic Lupus Erythematosus, cSLE)较成人往往更重，且可合并血液系统异常，例如贫血、血小板减少等。极少数SLE患儿可合并血栓性血小板减少性紫癜(Thrombotic Thrombocytopenic Purpura, TTP)，二者的临床表现相似、临床诊断困难，并且SLE合并TTP的病人，若治疗不及时病死率极高。本文报告一例本院救治成功的SLE合并TTP的病例。
Systemic lupus erythematosus (SLE) is a more common autoimmune disease and is often prone to lupus nephritis. Child-Onset Systemic Lupus Erythematosus, (cSLE) are often more severe than adult-onset and may be associated with abnormalities in the blood system, such as anemia and thrombocytopenia. A small number of children may be combined with thrombocytopenic purpura (TTP). There are many similarities, which make clinical diagnosis difficult, and the mortality of patients with SLE combined with TTP is extremely high if not treated in time. This article reports a case of SLE with TTP that was successfully treated in our hospital.