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-  2017 

扩大刮除术治疗软骨母细胞瘤的疗效观察

DOI: doi:10.7507/1002-1892.201706068

Keywords: 软骨母细胞瘤, 扩大刮除术, 关节功能

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Abstract:

目的 探讨扩大刮除术治疗软骨母细胞瘤的疗效。 方法 回顾性分析 2011 年 1 月—2016 年 5 月,采用病灶扩大刮除术治疗的 37 例软骨母细胞瘤患者临床资料。男 24 例,女 13 例;年龄 12~30 岁,中位年龄 17 岁。原发患者 32 例,复发患者 5 例。患者均以局部疼痛为首发症状。病程 2~8 个月,平均 4.9 个月。病变部位:股骨远端 10 例,股骨近端 7 例,胫骨近端 9 例,肱骨近端 5 例,髌骨 2 例,距骨 1 例,跟骨 1 例,骨盆 2 例。根据良性骨肿瘤的 Enneking 分期均为 3 期。病灶长径为 1.2~6.9 cm,平均 3.2 cm。19 例病变累及骺板。 结果 术后切口均Ⅰ期愈合,无相关并发症发生。患者均获随访,随访时间 12~76 个月,平均 40.5 个月。末次随访时国际肌肉骨骼肿瘤学会(MSTS)评分为(27.5±1.4)分,与术前(18.5±1.9)分比较,差异有统计学意义(t=23.462,P=0.000)。术后 5 个月复发 1 例(2.7%)。X 线片复查示,6 例出现部分植骨吸收,但植骨区关节面未见明显塌陷。3 例骺板受累且病变位于膝关节周围者,出现肢体短缩畸形,但无内外翻畸形,膝关节活动未受影响。 结论 扩大刮除术治疗软骨母细胞瘤具有术后复发率低、肢体功能良好、骨骼发育畸形发生率低等优点,是治疗该疾病较好方法

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