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-  2016 

盐酸甲氧明恒速泵注在老年冠心病患者行非心脏手术麻醉管理中的应用 Applications of Methoxamine Hydrochloride Constant Speed Infusion by Micropump in Coronary Heart Disease Patients Undergoing Non-Cardiac Surgery

Keywords: 盐酸甲氧明,冠心病,全身麻醉,低血压

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Abstract:

目的:评价盐酸甲氧明恒速泵注应用于老年冠心病患者行非心脏手术麻醉的可行性,并初步探讨其安全性及预后。方法:选择老年冠心病患者行非心脏手术患者30例,随机分成两组:对照组诱导前后不给予任何血管活性药物,甲氧明组诱导前依照2μg/(kg·h)的剂量恒速泵注盐酸甲氧明;记录基础值、诱导后5min、手术开始30min、拔管后5min收缩压(SBP)、舒张压(DBP)及心率(HR)的变化情况、恶心呕吐发生率、围术期心肌缺血发生率及其呼吸暂停发生率。结果:两组老年患者一般状况、基础血压、心率均无差异(P>0.05)。诱导后5min对照组血压显著低于甲氧明组(P<0.05)。术后随访镇痛效果均良好,无麻醉及恶心呕吐等并发症。无心绞痛和心肌梗塞的发生。结论:甲氧明恒速泵注应用于老年冠心病患者行非心脏手术麻醉可使循环更平稳,对血压和心率影响更小,不良反应更少

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