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-  2016 

肺血栓栓塞症的危险因素 Risk Factors of Pulmonary Thromboembolism

Keywords: 肺血栓栓塞症,危险因素,溶栓治疗

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Abstract:

目的:分析肺血栓栓塞症(PTE)患者的危险因素。方法:回顾性地分析121例符合PTE诊断标准的住院患者的临床资料,这些数据包括患者的危险因素、治疗及预后等。结果:121例患者中平均年龄(62.0±14.7)岁,其中老年组(≥60岁)73例(60.3%),非老年组(<60岁)48例(39.7%)。老年患者(≥60岁)、手术、恶性肿瘤是PTE常见的危险因素,老年组危险因素主要是恶性肿瘤、既往脑卒中等,非老年组为手术、骨折或大创伤,其差异均有统计学意义(P<0.05)。17例(14.0%)进行溶栓治疗,100例(82.6%)进行抗凝治疗,病死率为8.3%。中危PTE患者溶栓与抗凝治疗的有效率无显著性差别(P>0.05);溶栓治疗出血并发症为30%,高于抗凝组(5.5%,P<0.05)。结论:PTE常见的危险因素是年龄≥60岁、手术、恶性肿瘤等,老年组与非老年组危险因素有区别,中危PTE患者溶栓或抗凝治疗需结合临床具体分析

References

[1]  米玉红.急性肺栓塞研究现状及研究热点[J].中华急诊医学杂志,2015,24(2):133-138.Mi YH.Research status and hotspots of acute pulmonary embolism[J].Chinese Journal of Emergency Medicine,2015,24(2):133-138.
[2]  Tapson VF.Advances in the diagnosis and treatment of acute pulmonary embolism[J].F1000 Medicine Reports,2012,4:9.
[3]  Bělohlávek J,Dytrych V,Linhart A.Pulmonary embolism,part I:Epidemiology,risk factors and risk stratification,pathophysiology,clinical presentation,diagnosis and nonthromboticpulmonary embolism[J].Exp Clin Cardiol,2013,18(2):129-138.
[4]  Lankeit M,Konstantinides S.Thrombolysis for pulmonary embolism:Past,present and future[J].Thromb Haemost,2010,103(5):877-883.
[5]  中华医学会心血管病学分会肺血管病学组.急性肺血栓栓塞症诊断治疗中国专家共识[J].中华内科杂志,2010,49(1):74-81.Chinese Society of Cardiology.Experts consensus of standard diagnosis and treatment in acute pulmonary embolism in China[J].Chinese Journal of Internal Medicine,2010,49(1):74-81.
[6]  Falanga A,Russo L.Epidemiology,risk and outcomes of venous thromboembolism in cancer[J].Hamostaseologie,2012,32(2):115-125.
[7]  李雪松,刘雅丽,刘惠林.153例急性肺栓塞溶栓与单纯抗凝疗效评价[J].中国危重病急救医学,2012,24(10):632-633.Li XS,Liu YL,Liu HL.Effect of thrombolysis therapy versus anticoagulation alone in 153cases of patients with acute pulmonary embolism[J].Chinese Critical Care Medicine,2012,24(10):632-33.
[8]  Tapson VF.Acute Pulmonary Embolism[J].The New England Journal of Medicine,2008,358(10):1 037-1 052.
[9]  Torbicki A,Perrier A,Konstantinides S,et al.Guidelines on the diagnosis and management of acute pulmonary embolism:the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology(ESC)[J].European Heart Journal,2008,29(18):2 276-2 315.
[10]  Cohen AT,Agnelli G,Anderson FA,et al.Venous thromboembolism in Europe.The number of VTE events and associated morbidity and mortality[J].Thrombosis and Haemostasis,2007,98:756-764.
[11]  Yang YH,Liang LR,Zhai ZG,et al.Pulmonary embolism incidence and fatality trends in Chinese hospitals from 1997to 2008:A multicenter registration study[J].PLoS One,2011,6(11):1-7.
[12]  郝敏,佟丽,程兆忠.急性肺栓塞合并深静脉血栓患者不同治疗方案临床分析[J].国际呼吸杂志,2012,32(8):578-581.Hao M,Tong L,Cheng ZZ.Clinical analysis of different regimens on acute pulmonary thromboembolism with deep venom thrombosis[J].International Journal of Respiration,2012,32(8):578-581.
[13]  程显声,何建国,柳志红,等.对急性肺栓塞中危患者溶栓疗法的建议[J].中华医学杂志,2011,91(32):2 236-2 238.Cheng XS,He JG,Liu ZH,et al.The suggestion of thrombolytic therapy for intermediate risk patients with acute pulmonary embolism[J].National Medical Journal of China,2011,91(32):2 236-2 238.
[14]  Heit JA.Epidemiology of venous thromboembolism[J].Nature Reviews Cardiology,2015,12(8):464-474.
[15]  Noble S,Pasi J.Epidemiology and pathophysiology of cancer-associated thrombosis[J].Br J Cancer,2010,102Suppl 1:S2-S9.
[16]  Fasullo S,Scalzo S,Maringhini G,et al.Six-month echocardiographic study in patients with submassive pulmonary embolism and right ventricle dysfunction:Comparison of thrombolysis with heparin[J].The American Journal of the Medical Sciences,2011,341(1):33-39.

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