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OALib Journal期刊
ISSN: 2333-9721
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2型糖尿病患者血清血管性血友病因子、血小板活化因子水平与糖尿病肾病的关系
, PP. 729-731
Keywords: 2型糖尿病,糖尿病肾病,血管性血友病因子,血小板活化因子
Abstract:
目的探讨2型糖尿病患者尿微量白蛋白(ualb)、血管性血友病因子(vwf)、血小板活化因子(paf)变化及临床意义。方法研究对象分5组:糖尿病肾病患者(a组),2型糖尿病无肾病并发症患者(b组)、糖耐量受损者(c组)、糖耐量正常的2型糖尿病患者一级亲属(d组)、无2型糖尿病家族史糖耐量正常受试者(e组),每组30例,分别检测ualb、vwf、paf水平,并进行统计分析。结果a组ualb、paf含量明显高于其他4组(p<0.01),其他4组间ualb、paf差异无显著性(p>0.05);a组vwf含量与b、c、d组比较差异有显著性(p<0.05)。结论2型糖尿病微血管并发症患者存在肾功能损害和血小板活化,两者变化同步,提示其血管损伤与paf含量升高有关。
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