Oliveira PH, Prather KJ, Prazeres DM, Monteiro GA. Structural instability of plasmid biopharmaceuticals:challenges and implications[J]. Trends Biotechnol, 2009, 27:503-513.
[2]
Jeong SO, Shin SC, Jong-Kee Y, et al. Construction of various bacteriophage λ mutants for stable and efficient production of recombinant protein in Escherichia coli[J]. Process Biochemistry, 2007, 42?:486-490.
[3]
Vidal L, Pinsach J, Striedner G, et al. Development of an antibiotic-free plasmid selection system based on glycine auxotrophy for recombinant protein overproduction in Escherichia coli[J]. J Biotechnol, 2008, 134:127-162.
[4]
Nikel PI, de Lorenzo V. Implantation of unmarked regulatory and metabolic modules in Gram-negative bacteria with specialised mini-transposon delivery vectors[J]. J Biotechnol, 2013, 163?:143-154.
Filomena S, Jo?o AQ, Fernanda CD. Evaluating metabolic stress and plasmid stability in plasmid DNA production by Escherichia coli[J]. Biotechnol Adv, 2012, 30?:691-708.
[7]
Thumann G, Stocker M, Maltusch C, et al. High efficiency non-viral transfection of retinal and iris pigment epithelial cells with pigment epithelium-derived factor[J]. Gene Ther, 2010, 17:181-189.
[8]
Yau SY, Keshavarz-Moore E, Ward J. Host strain influences on supercoiled plasmid DNA production in Escherichia coli:implications for efficient design of large-scale processes[J]. Biotechnol Bioeng, 2008, 101:529-572.
[9]
Ertl PF, Thomsen LL. Technical issues in construction of nucleic acid vaccines[J]. Methods, 2003, 31:199-206.
[10]
Hadj Kacem B, Gargouri J, Gargouri A. In vitro direct repeats-mediated deletion during PCR amplification[J]. Mol Biotechnol, 2008, 40:39-45.
[11]
Valesova R, Stepanek V, Vecerek B, Kyslik P. IS2-mediated re-arrangement of the promoter sequence suppresses metabolic burden of the recombinant plasmid[J]. Folia Microbiol(Praha), 2005, 50:275-282.
[12]
Oliveira PH, Prazeres DM, Monteiro GA. Deletion formation mutations in plasmid expression vectors are unfavored by runaway amplification conditions and differentially selected under kanamycin stress[J]. J Biotechnol, 2009, 143:231-238.
[13]
Xu J, Li W, Wu J, et al. Stability of plasmid and expression of a recombinant gonadotropin-releasing hormone(GnRH)vaccine in Escherichia coli[J]. Appl Microbiol Biotechnol, 2006, 73:780-788.
[14]
Goyal D, Sahni G, Sahoo DK. Enhanced production of recombinant streptokinase in Escherichia coli using fed-batch culture[J]. Bioresour Technol, 2009, 100:4468-4541.
[15]
Krishna Rao DV, Ramu CT, Rao JV, et al. Impact of dissolved oxygen concentration on some key parameters and production of rhG-CSF in batch fermentation[J]. J Ind Microbiol Biotechnol, 2008, 35:991-1000.
[16]
Chen HC, Hwang CF, Mou DG. High-density Escherichia coli cultivation process for hyperexpression of recombinant porcine growth hormone[J]. Enzyme Microb Technol, 1992, 14:321-326.
[17]
O''Kennedy RD, Ward JM, Keshavarz-Moore E. Effects of fermentation strategy on the characteristics of plasmid DNA production[J]. Biotechnol Appl Biochem, 2003, 37:83-90.
[18]
O''Kennedy RD, Baldwin C, Keshavarz-Moore E. Effects of growth medium selection on plasmid DNA production and initial processing steps[J]. J Biotechnol, 2000, 76:175-183.
[19]
Pristas P, Ivan J, Javorsky P. Structural instability of small rolling circle replication plasmids from Selenomonas ruminantium[J]. Plasmid, 2010, 64:74-81.
[20]
Ribeiro SC, Monteiro GA, Prazeres DM. The impact of polyadenyla-tion signals on plasmid nuclease-resistance and transgene expression[J]. J Gene Med, 2007, 9:392-402.
[21]
Bi X, Liu LF. DNA rearrangement mediated by inverted repeats[J]. Proc Natl Acad Sci USA, 1996, 93:819-823.
[22]
Haddadin FT, Harcum SW. Transcriptome profiles for high-cell-density recombinant and wild-type Escherichia coli[J]. Biotechnol Bioeng, 2005, 90:127-153.
[23]
Summers DK, Sherratt DJ. Multimerization of high copy number plasmids causes instability:CoIE1 encodes a determinant essential for plasmid monomerization and stability[J]. Cell, 1984, 36:1097-1103.
[24]
O''Kennedy RD, Patching JW. Effects of medium composition and nutrient limitation on loss of the recombinant plasmid pLG669-z and beta-galactosidase expression by Saccharomyces cerevisiae[J]. J Ind Microbiol Biotechnol, 1997, 18:319-325.
[25]
Adamcik J, Viglasky V, Valle F, et al. Effect of bacteria growth temperature on the distribution of supercoiled DNA and its thermal stability[J]. Electrophoresis, 2002, 23:3300-3309.
[26]
Higgins CF, Dorman CJ, Stirling DA, et al. A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli[J]. Cell, 1988, 52:569-584.
[27]
Freitas SS, Azzoni AR, Santos JA, et al. On the stability of plasmid DNA vectors during cell culture and purification[J]. Mol Biotechnol, 2007, 36:151-158.
[28]
Sabido A, Martínez LM, de Anda R, et al. A novel plasmid vector designed for chromosomal gene integration and expression:Use for developing a genetically stable Escherichia coli melanin production strain [J]. Plasmid, 2012, 69:16-23.
Mairhofer J, Pfaffenzeller I, Merz D, Grabherr R. A novel antibiotic free plasmid selection system:advances in safe and efficient DNA therapy[J]. Biotechnol J, 2008, 3:83-91.
[31]
Goh S, Good L. Plasmid selection in Escherichia coli using an endogenous essential gene marker[J]. BMC Biotechnol, 2008, 8:61-69.
[32]
Philip DS, Sarovich DS, Pemberton JM. pPSY:A vector for the stable cloning and expression of streptomycete single gene phenotypes in Escherichia coli[J] . Plasmid, 2008, 60?:53-58.
Sousa F, Prazeres DM, Queiroz JA. Improvement of transfection efficiency by using supercoiled plasmid DNA purified with arginine affinity chromatography[J]. J Gene Med, 2009, 11:79-88.
[36]
Martí L, Enric S, Antoni C, et al. IPTG limitation avoids metabolic burden and acetic acid accumulation in induced fed-batch cultures of Escherichia coli M15 under glucose limiting conditions[J]. Biochem Eng J, 2013, 70:78-83.