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脱氧雪腐镰刀菌烯醇对肠道屏障的影响及其作用机制

DOI: 10.3969/j.issn.1006-267x.2013.01.002

Keywords: 脱氧雪腐镰刀菌烯醇,肠上皮细胞,肠道屏障

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Abstract:

脱氧雪腐镰刀菌烯醇(DON)对食物和饲料的污染是一个全球性的问题,它不仅影响了人类和动物的健康,还造成了严重的经济损失。肠道是机体抵御病原体和毒素入侵的第1道屏障,近年来的研究表明DON不仅抑制了肠道对营养物质的吸收,还影响了肠道屏障和细胞紧密连接,并改变了肠道微生物组成。本文将围绕DON对肠道屏障的影响及其作用机制进行综述。

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