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肺腺癌与鳞癌螺旋CT灌注参数的对照研究

, PP. 492-494

Keywords: X线计算机,灌注成像,微血管密度,肺癌

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Abstract:

目的探讨多层螺旋CT(MSCT)灌注成像对肺癌病理分型诊断的应用价值。方法利用16层螺旋CT灌注成像技术研究经病理证实的40例周围型肺癌,其中腺癌25例,鳞癌15例,记录术前MSCT灌注成像参数血流量(BF)、血容量(BV)、平均通过时间(MTT)和毛细血管表面通透性(PS)。对40例肺癌组织标本采用免疫组织化学染色法测定肿瘤微血管密度(MVD)。对腺癌组与鳞癌组的MVD计数及CT各项灌注参数进行对照研究。结果肺腺癌MVD计数高于鳞癌,二者间差异有统计学意义(P<0.05)。肺癌各项灌注参数间差异均无统计学意义。结论CT灌注参数对于周围型肺癌的病理分型尚无明确诊断价值。

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