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913株凝固酶阴性葡萄球菌临床分离株耐药性分析

, PP. 53-55

Keywords: 凝固酶阴性葡萄球菌,耐药性,耐甲氧西林凝固酶阴性葡萄球菌

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Abstract:

目的了解2008-2011年广州医学院第二附属医院临床分离的凝固酶阴性葡萄球菌感染状况及其耐药性变迁,为临床合理使用抗菌药物提供依据。方法凝固酶阴性葡萄球菌培养与鉴定严格按照《全国临床检验操作规程》进行;药敏试验采用K-B法,结果依据NCCLS最新折点进行评价。结果共检出革兰阳性球菌3319株,其中凝固酶阴性葡萄球菌913株,占革兰阳性球菌的27.51%。耐甲氧西林凝固酶阴性葡萄球菌647株,占凝固酶阴性葡萄球菌的70.86%。CNS对青霉素耐药率最高,高达99.1%,对克林霉素、复方新诺明、庆大霉素、喹诺酮类药的耐药率次之,对利福平、夫西地酸、万古霉素等耐药率均较低。结论CNS对多种抗菌药物的耐药率不断提高,应及时监测,指导临床医师合理使用抗菌药物,延缓耐药菌株的产生,同时加强控制感染工作,阻止耐药菌株的传播。

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