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脑卒中患者颈动脉粥样斑块发生与Hcy水平的相关性

, PP. 975-977

Keywords: 缺血性脑卒中,颈动脉粥样硬化,同型半胱氨酸

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Abstract:

目的探讨缺血性脑卒中患者颈动脉粥样斑块发生情况与血清同型半胱氨酸水平的相关性。方法对缺血性脑卒中住院患者,应用彩色多普勒超声检测颈部血管内中膜厚度及斑块形成情况,并同期检测患者血清同型半胱氨酸浓度。结果236例病例组患者中,183例检出颈动脉粥样硬化斑块,发生率为77.54%;260例对照组检出颈动脉粥样硬化斑块60例,发生率为23.07%,缺血性脑卒中组粥样硬化斑块发生率明显高于对照组(P<0.01)。缺血性脑卒中患者平均血清同型半胱氨酸水平显著高于对照组(P<0.05),且同型半胱氨酸水平与颈动脉粥样硬化的程度及硬化斑块的性质相关(P<0.05)。结论缺血性脑卒中患者颈动脉粥样硬化斑块发生与血清同型半胱氨酸水平之间有密切的相关性。

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