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喹乙醇对蚯蚓的毒理学研究

Keywords: 喹乙醇,蚯蚓,急性毒性,过氧化氢酶

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Abstract:

以滤纸染毒和溶液染毒法研究了喹乙醇对蚯蚓的急性毒性效应以及对其生长的影响。结果表明,滤纸染毒和溶液染毒48h的致死中浓度(LC50)分别为1.02mg.cm-2和>4000mg.L-1,喹乙醇能引起蚯蚓的形态病理变化。低浓度喹乙醇(500、1000mg.kg-1)对蚯蚓的体重增长率没有显著影响(P>0.05),高浓度喹乙醇(3000、5000mg.kg-1)能极显著降低蚯蚓体重增长率(P<0.01)。检测暴露喹乙醇14d的蚯蚓体和不同部位的过氧化氢酶(CAT)活性,结果发现,高浓度喹乙醇能显著抑制蚯蚓体及其前部和中部CAT的活性,低浓度喹乙醇只对蚯蚓前部的CAT活性表现出显著抑制(P<0.05)。

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