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人体慢性低剂量农药暴露生物学监测研究进展

DOI: 10.11847/zgggws2015-31-07-12, PP. 900-903

Keywords: 农药暴露,慢性低剂量,生物学监测

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Abstract:

?人体慢性低剂量农药暴露的生物学监测对于评估农药暴露对人体健康的影响有重要意义。生物学监测的标本来源除了目前使用广泛的尿液及血液标本,唾液、汗水、头发等也被用作农药暴露的生物学监测。监测的指标可以直接检测各种生物标本中的农药本身的化学物质及其代谢产物的含量,还可以通过间接指标如酶学、神经递质、DNA、蛋白质进行检测。选择合适的生物学监测方法可以为正确评估人体农药暴露提供有力的依据。本文对目前人体慢性低剂量农药暴露的生物学监测方法进行综述。

References

[1]  Hudson G,Miller GG,Seikel K.Regulations,policies,and guidelines addressing environmental exposures in early learning environments:a review[J].J Environ Health,2014,76(7):24-34.
[2]  Bulgaroni V,Rovedatti MG,Sabino G,et al.Organophosphate pesticide environmental exposure:analysis of salivary cholinesterase and carboxilesterase activities in preschool children and their mothers[J].Environ Monit Assess,2012,184:3307-3314.
[3]  Albertini R,Bird M,Doerrer N,et al.The use of biomonitoring data in exposure and human health risk assessments[J].Environ Health Perspect,2006,114(11):1755-1762.
[4]  Egeghy PP,Cohen HE,Tulve NS,et al.Review of pesticide urinary biomarker measurements from selected US EPA children''s observational exposure studies[J].Int J Environ Res Public Health,2011,8(5):1727-1754.
[5]  Arcury TA,Grzywacz JG,Isom S,et al.Seasonal variation in the measurement of urinary pesticide metabolites among Latino farmworkers in eastern North Carolina[J].Int J Occup Environ Health,2009,15(4):339-350.
[6]  Barr DB,Angerer J.Potential uses of biomonitoring data:a case study using the organophosphorus pesticides chlorpyrifos and malathion[J].Environ Health Perspect,2006,114(11):1763-1769.
[7]  Ross JH,Driver JH,Cochran RC,et al.Could pesticide toxicology studies be more relevant to occupational risk assessment?[J].Ann Occup Hyg,2001,45(Suppl 1):S5-17.
[8]  Muniz JF,Mccauley L,Scherer J,et al.Biomarkers of oxidative stress and DNA damage in agricultural workers:a pilot study[J].Toxicol Appl Pharmacol,2008,227(1):97-107.
[9]  Lakind JS,Barraj L,Tran N,et al.Environmental chemicals in people:challenges in interpreting biomonitoring information[J].Environ Health,2008,70(9):61-64.
[10]  Timchalk C,Poet TS,Kousba AA,et al.Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure:analysis of lead or organophosphate insecticide in saliva[J].Toxicol Environ Health A,2004,67(8-10):635-650.
[11]  Timchalk C,Campbell JA,Liu G,et al.Development of a non-invasive biomonitoring approach to determine exposure to the organophosphorus insecticide chlorpyrifos in rat saliva[J].Toxicol Appl Pharmacol,2007,219(2-3):217-225.
[12]  Tutudaki M,Tsatsakis AM.Pesticide hair analysis:development of a GC-NCI-MS method to assess chronic exposure to diazinon in rats[J].J Anal Toxicol,2005,29(8):805-809.
[13]  Ostrea EJ,Villanueva-Uy E,Bielawski D,et al.Analysis of house dust and children''s hair for pesticides:a comparison of markers of ongoing pesticide exposure in children[J].J Bioanal Biomed,2011,4.DOI:10.4172/1948-593x.1000057.
[14]  Ostrea EM,Morales V,Ngoumgna E,et al.Prevalence of fetal exposure to environmental toxins as determined by meconium analysis[J].Neurotoxicology,2002,23(3):329-339.
[15]  Ostrea EJ,Villanueva-Uy E,Bielawski DM,et al.Maternal hair-an appropriate matrix for detecting maternal exposure to pesticides during pregnancy[J].Environ Res,2006,101(3):312-322.
[16]  Rosenberg NM,Queen RM,Stamper JH.Sweat-patch test for monitoring pesticide absorption by airblast applicators[J].Bull Environ Contam Toxicol,1985,35(1):68-72.
[17]  Brunet BR,Barnes AJ,Choo RE,et al.Monitoring pregnant women''s illicit opiate and cocaine use with sweat testing[J].Ther Drug Monit,2010,32(1):40-49.
[18]  Bush DM.The US Mandatory Guidelines for Federal Workplace Drug Testing Programs:current status and future considerations[J].Forensic Sci Int,2008,174(2-3):111-119.
[19]  Koutroulakis D,Sifakis S,Tzatzarakis MN,et al.Dialkyl phosphates in amniotic fluid as a biomarker of fetal exposure to organophosphates in Crete,Greece;association with fetal growth[J].Reprod Toxicol,2014,46C:98-105.
[20]  Ngo MA,O''Malley M,Maibach HI.Percutaneous absorption and exposure assessment of pesticides[J].J Appl Toxicol,2010,30(2):91-114.
[21]  Gralewicz S,Swiercz R,Lutz P,et al.Effects of stress pretreatment on the dynamics of blood cholinesterase activity after exposure to an organophosphorus pesticide in the rat[J].Ann Agric Environ Med,2010,17(1):65-71.
[22]  De Silva HJ,Samarawickrema NA,Wickremasinghe AR.Toxicity due to organophosphorus compounds:what about chronic exposure?[J].Trans R Soc Trop Med Hyg,2006,100(9):803-806.
[23]  Beltran KS,Pocsidio GN.Acetylcholinesterase activity in Corbicula fluminea Mull.,as a biomarker of organophosphate pesticide pollution in Pinacanauan River,Philippines[J].Environ Monit Assess,2010,165(1-4):331-340.
[24]  Choi JY,Yu J,Yang DB,et al.Acetylthiocholine(ATC)-cleaving cholinesterase(ChE)activity as a potential biomarker of pesticide exposure in the Manila clam,Ruditapes philippinarum,of Korea[J].Mar Environ Res,2011,71(3):162-168.
[25]  Timchalk C,Poet TS,Kousba AA,et al.Noninvasive biomonitoring approaches to determine dosimetry and risk following acute chemical exposure:analysis of lead or organophosphate insecticide in saliva[J].J Toxicol Environ Health A,2004,67(8-10):635-650.
[26]  Ng V,Koh D,Wee A,et al.Salivary acetylcholinesterase as a biomarker for organophosphate exposure[J].Occup Med(Lond),2009,59(2):120-122.
[27]  Xie S,Borazjani A,Hatfield MJ,et al.Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides:role of carboxylesterases 1 and 2[J].Chem Res Toxicol,2010,23(12):1890-1904.
[28]  Bulgaroni V,Rovedatti MG,Sabino G,et al.Organophosphate pesticide environmental exposure:analysis of salivary cholinesterase and carboxilesterase activities in preschool children and their mothers[J].Environ Monit Assess,2012,184(5):3307-3314.
[29]  方国飞.三种农药对红裸须摇蚊毒力和羧酸酯酶活性的影响[J].生态学报,2011(17):4914-4918.
[30]  Lee DH,Jacobs DJ.Serum gamma-glutamyltransferase:new insights about an old enzyme[J].J Epidemiol Community Health,2009,63(11):884-886.
[31]  Debord J,Laubarie C,Dantoine T.Microcalorimetric study of the inhibition of butyrylcholinesterase by carbamates[J].Anal Biochem,2008,373(2):247-252.
[32]  Hofmann JN,Keifer MC,Furlong CE,et al.Serum cholinesterase inhibition in relation to paraoxonase-1(PON1)status among organophosphate-exposed agricultural pesticide handlers[J].Environ Health Perspect, 2009,117(9):1402-1408.
[33]  Kapka-Skrzypczak L,Cyranka M,Skrzypczak M,et al.Biomonitoring and biomarkers of organophosphate pesticides exposure-state of the art[J].Ann Agric Environ Med, 2011,18(2):294-303.
[34]  Hreljac I,Zajc I,Lah T,et al.Effects of model organophosphorous pesticides on DNA damage and proliferation of HepG2 cells[J].Environ Mol Mutagen,2008,49(5):360-367.
[35]  Bumroongkit K,Rannala B,Traisathit P,et al.TP53 gene mutations of lung cancer patients in upper northern Thailand and environmental risk factors[J].Cancer Genet Cytogenet,2008,185(1):20-27.
[36]  Lane DP.On the expression of the p53 protein in human cancer[J].Mol Biol Rep,1994,19(1):23-29.
[37]  Cohen M.Environmental toxins and health—the health impact of pesticides[J].Aust Fam Physician,2007,36(12):1002-1004.
[38]  Povey AC.Gene-environmental interactions and organophosphate toxicity[J].Toxicology,2010,278(3):294-304.
[39]  李君,常永丽,蒋守芳,等.有机氯农药残留及GSTM1基因与女性乳腺癌关系[J].中国公共卫生,2012,26(5):558-560.
[40]  Zeljezic D,Garaj-Vrhovac V.Chromosomal aberration and single cell gel electrophoresis(Comet)assay in the longitudinal risk assessment of occupational exposure to pesticides[J].Mutagenesis,2001,16(4):359-363.
[41]  Collins AR,Oscoz AA,Brunborg G,et al.The comet assay:topical issues[J].Mutagenesis,2008,23(3):143-151.
[42]  Valverde M,Rojas E.Environmental and occupational biomonitoring using the Comet assay[J].Mutat Res,2009,681(1):93-109.
[43]  Tucker JD,Moore DN,Ramsey MJ,et al.Multi-endpoint biological monitoring of phosphine workers[J].Mutat Res,2003,536(1-2):7-14.
[44]  Windham GC,Titenko-Holland N,Osorio AM,et al.Genetic monitoring of malathion-exposed agricultural workers[J].Am J Ind Med,1998,33(2):164-174.

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