红药苯乙醇苷类化学成分的研究

目的:分离鉴定红药干燥茎的化学成分。方法:甲醇提取,硅胶、SephadexLH-20及ODS柱色谱分离,采用NMR和MS等方法确定化合物的结构。结果:分离鉴定了5个苯乙醇苷类化合物,分别为3,4-dihydroxyphenylalcohol-β-D-glucopyranoside(1),3,4-dihydroxyphenylalcohol-6-O-caffeoyl-β-D-glucopyranoside(calceolariosideB)(2),3,4-di-hydroxyphenylalcohol-β-D-glucopyranosyl-(1→3)-6-O-caffeoyl-β-D-glucopyranoside(plantainosideD)(3),3,4-dihydroxyphenylalcohol-β-D-glucopyranosyl-(1→3)-4-O-caffeoyl-β-D-glucopyranoside(plantamajoside)(4),3,4-dihydroxyphenylalcohol-β-D-glucopyranosyl-(1→3)-6-O-feruloyl-β-D-glucopyranoside(scrosideE)(5)。结论:化合物3,5为首次从该科植物中得到,化合物1,2,4为首次从该属植物中得到。