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藁本内酯药理学和药代动力学研究进展

Keywords: 藁本内酯,药理学,药物代谢动力学

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Abstract:

藁本内酯在川芎、当归等伞形科植物中含量较高,在1%左右,是主要活性成分之一,并具有多种与药效相关的药理活性。目前藁本内酯已引起人们广泛关注,对其研究报道越来越多,是一个很有发展前途的化合物。文中就近年来藁本内酯在神经保护、舒张血管、抗癌抗肿瘤、镇痛消炎等方面的药理作用以及吸收、分布、代谢和排泄等方面的药物代谢动力学研究进展进行综述,为藁本内酯的进一步研究开发提供依据。

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