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交流阻抗法评价含硅PEO陶瓷膜在SBF模拟液中的生物活性

, PP. 312-318

Keywords: 纯钛,PEO,陶瓷膜,EIS,生物活性

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Abstract:

利用电化学阻抗谱原位监测浸泡在人体模拟液(SBF)中生物活性PEO陶瓷膜表面上羟基磷灰石(HA)的形核和生长过程,评价PEO陶瓷膜的体外生物活性.结果表明,在SBF模拟液中浸泡7d后,含硅PEO陶瓷膜阻抗谱的高频段出现一个新的时间常数;同时,最外层氧化膜电阻值显著增加,说明HA晶粒在膜层表面形核并快速生长;基准PEO陶瓷膜在SBF模拟液中浸泡18d后,最外层电阻值才有上升趋势,而且增长速度非常缓慢.含硅PEO陶瓷膜中CaSiO3和SiO2为羟基磷灰石的沉积提供了更多的异质形核点,因此大大提高其生物活性.

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