1 Chen X. Small RNAs: secrets and surprises of the genome. Plant J, 2010, 61: 941-958？？
[2]
2 Ghildiyal M, Zamore P D. Small silencing RNAs: an expanding universe. Nat Rev Genet, 2009, 10: 94-108？？
[3]
3 Chapman E J, Carrington J C. Specialization and evolution of endogenous small RNA pathways. Nat Rev Genet, 2007, 8: 884-896？？
[4]
4 Hamilton A J, Baulcombe D C. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science, 1999, 286:950-952？？
[5]
5 Burgyan J. Role of silencing suppressor proteins. Methods Mol Biol, 2008, 451: 69-79？？
[6]
6 Ding S-W, Voinnet O. Antiviral immunity directed by small RNAs. Cell, 2007, 130: 413-426？？
[7]
7 Voinnet O, Pinto Y M, Baulcombe D C. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants.Proc Natl Acad Sci USA, 1999, 96: 14147-14152？？
[8]
8 Szittya G, Moxon S, Pantaleo V, et al. Structural and functional analysis of viral siRNAs. PLoS Pathog, 2010, 6: e1000838？？
[9]
9 Qu F. Antiviral role of plant-encoded RNA-dependent RNA polymerases revisited with deep sequencing of small interfering RNAs of virusorigin. Mol Plant Microbe Interact, 2010, 23: 1248-1252？？
[10]
10 Donaire L, Wang Y, Gonzalez-Ibeas D, et al. Deep-sequencing of plant viral small RNAs reveals effective and widespread targeting of viralgenomes. Virology, 2009, 392: 203-214？？
[11]
11 Donaire L, Barajas D, Martinez-Garcia B, et al. Structural and genetic requirements for the biogenesis of tobacco rattle virus-derived smallinterfering RNAs. J Virol, 2008, 82: 5167-5177？？
[12]
12 Pantaleo V, Szittya G, Burgyan J. Molecular bases of viral RNA targeting by viral small interfering RNA-programmed RISC. J Virol, 2007,81: 3797-3806？？
[13]
13 Molnar A, Csorba T, Lakatos L, et al. Plant virus-derived small interfering RNAs originate predominantly from highly structuredsingle-stranded viral RNAs. J Virol, 2005, 79: 7812-7818？？
[14]
14 Wang X B, Wu Q, Ito T, et al. RNAi-mediated viral immunity requires amplification of virus-derived siRNAs in Arabidopsis thaliana. ProcNatl Acad Sci USA, 2010, 107: 484-489？？
[15]
30 Bouche N, Lauressergues D, Gasciolli V, et al. An antagonistic function for Arabidopsis DCL2 in development and a new function forDCL4 in generating viral siRNAs. EMBO J, 2006, 25: 3347-3356？？
[16]
31 Deleris A, Gallego-Bartolome J, Bao J, et al. Hierarchical action and inhibition of plant Dicer-like proteins in antiviral defense. Science,2006, 313: 68-71？？
[17]
32 Blevins T, Rajeswaran R, Shivaprasad P V, et al. Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing.Nucleic Acids Res, 2006, 34: 6233-6246？？
[18]
33 Yoshikawa M, Peragine A, Park M Y, et al. A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. Genes Dev, 2005, 19:2164-75？？
[19]
34 Vazquez F, Vaucheret H, Rajagopalan R, et al. Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. MolCell, 2004, 16:69-79
[20]
35 Peragine A, Yoshikawa M, Wu G, et al. SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production oftrans-acting siRNAs in Arabidopsis. Genes Dev, 2004, 18: 2368-79？？
[21]
36 Baulcombe D. RNA silencing in plants. Nature, 2004, 431: 356-363？？
[22]
37 Harvey J J W, Lewsey M G, Patel K, et al. An antiviral defense role of AGO2 in plants. PLoS ONE, 2011, 6: e14639？？
[23]
38 Takeda A, Iwasaki S, Watanabe T, et al. The mechanism selecting the guide strand from small RNA duplexes is different among Argonauteproteins. Plant Cell Physiol, 2008, 49: 493-500？？
[24]
39 Qu F, Ye X, Morris T J. Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathwaynegatively regulated by DCL1. Proc Natl Acad Sci USA, 2008, 105: 14732-14737
[25]
40 Wang X B, Jovel J, Udomporn P, et al. The 21-nucleotide, but not 22-nucleotide, viral secondary small interfering RNAs direct potentantiviral defense by two cooperative Argonautes in Arabidopsis thaliana. Plant Cell, 2011, 23: 1625-1638
[26]
41 Montgomery T A, Howell M D, Cuperus J T, et al. Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3trans-acting siRNA formation. Cell, 2008, 133: 128-141？？
[27]
42 Mi S, Cai T, Hu Y, et al. Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5'' terminal nucleotide. Cell, 2008,133: 116-127？？
[28]
43 Simon-Mateo C, Garcia J A. MicroRNA-guided processing impairs Plum Pox Virus replication, but the virus readily evolves to escape this silencing mechanism. J Virol, 2006, 80: 2429-2436？？
[29]
44 Li H, Li W X, Ding S W. Induction and suppression of RNA silencing by an animal virus. Science, 2002, 296: 1319-1321？？
[30]
45 Diaz-Pendon J A, Li F, Li W-X, et al. Suppression of antiviral silencing by cucumber mosaic virus 2b protein in Arabidopsis is associatedwith drastically reduced accumulation of three classes of viral small interfering RNAs. Plant Cell 2007, 19: 2053-2063？？
[31]
46 Martin-Hernandez A M, Baulcombe D C. Tobacco rattle virus 16-kilodalton protein encodes a suppressor of RNA silencing that allowstransient viral entry in meristems. J Virol, 2008, 82: 4064-4071？？
[32]
47 Du Q S, Duan C G, Zhang Z H, et al. DCL4 targets Cucumber mosaic virus satellite RNA at novel secondary structures. J Virol, 2007, 81:9142-9151？？
[33]
48 Zhu H, Duan C-G, Hou W-N, et al. Satellite RNA-derived satsiR-12 targeting the 3′UTR of Cucumber mosaic virus triggers viral RNAs fordegradation. J Virol, 2011, 85: 13384-13397？？
[34]
62 Roth B M, Pruss G J, Vance V B. Plant viral suppressors of RNA silencing. Virus Res, 2004, 102: 97-108？？
[35]
63 Manfre A. Importance of coat protein and RNA silencing in satellite RNA/virus interactions. Virology, 2008, 379: 161-167？？
[36]
64 Zhang F, Simon A E. Enhanced viral pathogenesis associated with a virulent mutant virus or a virulent satellite RNA correlates withreduced virion accumulation and abundance of free coat protein. Virology, 2003, 312: 8-13？？
[37]
65 Raja P, Sanville B C, Buchmann R C, et al. Viral genome methylation as an epigenetic defense against geminiviruses. J Virol, 2008, 82:8997-9007？？
[38]
66 Yang X, Xie Y, Raja P, et al. Suppression of methylation-mediated transcriptional gene silencing by βC1-SAHH protein interaction duringgeminivirus-betasatellite infection. PLoS Pathog, 2011, 7: e1002329？？
[39]
67 Blevins T, Rajeswaran R, Aregger M, et al. Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus inplant defense and viral counter-defense. Nucleic Acids Res, 2011, 39: 5003-5014？？
[40]
60 Li W X, Ding S W. Viral suppressors of RNA silencing. Curr Opin Biotechnol, 2001, 12: 150-154？？
[41]
61 Moissiard G, Voinnet O. Viral suppression of RNA silencing in plants. Mol Plant Pathol, 2004, 5: 71-82？？
[42]
15 Garcia-Ruiz H, Takeda A, Chapman E J, et al. Arabidopsis RNA-dependent RNA polymerases and Dicer-like proteins in antiviral defenseand small interfering RNA biogenesis during Turnip Mosaic Virus infection. Plant Cell, 2010, 22: 481-496？？
[43]
16 Qi X, Bao F S, Xie Z. Small RNA deep sequencing reveals role for Arabidopsis thaliana RNA-dependent RNA polymerases in viral siRNAbiogenesis. PLoS ONE, 2009, 4: e4971？？
[44]
17 Azevedo J, Garcia D, Pontier D, et al. Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GWrepeat protein. Genes Dev, 2010, 24: 904-915？？
[45]
18 Zhang X, Yuan Y R, Pei Y, et al. Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity tocounter plant defense. Genes Dev, 2006, 20: 3255-3268？？
[46]
19 Pantaleo V, Burgyan J. Cymbidium ringspot virus harnesses RNA silencing to control the accumulation of virus parasite satellite RNA. JVirol, 2008, 82: 11851-11858？？
[47]
20 Golem S, Culver J N. Tobacco mosaic virus induced alterations in the gene expression profile of Arabidopsis thaliana. Mol Plant MicrobeInteract, 2003, 16: 681-688？？
[48]
21 Whitham S A, Yang C, Goodin M M. Global impact: elucidating plant responses to viral infection. Mol Plant Microbe Interact, 2006, 19:1207-15？？
[49]
22 Agudelo-Romero P, Carbonell P, de la Iglesia F, et al. Changes in the gene expression profile of Arabidopsis thaliana after infection withTobacco etch virus. Virol J, 2008, 5: 92？？
[50]
23 Havelda Z, Varallyay E, Valoczi A, et al. Plant virus infection-induced persistent host gene downregulation in systemically infected leaves.Plant J, 2008, 55: 278-88？？
[51]
24 Ahlquist P. RNA-dependent RNA polymerases, viruses, and RNA silencing. Science, 2002, 296: 1270-1273？？
[52]
25 den Boon J A, Ahlquist P. Organelle-like membrane compartmentalization of positive-strand RNA virus replication factories. Annu RevMicrobiol, 2010, 64: 241-56？？
[53]
26 Moissiard G, Voinnet O. RNA silencing of host transcripts by cauliflower mosaic virus requires coordinated action of the four ArabidopsisDicer-like proteins. Proc Natl Acad Sci USA, 2006, 103: 19593-19598？？
[54]
27 Vanitharani R, Chellappan P, Fauquet C M. Geminiviruses and RNA silencing. Trends Plant Sci, 2005, 10: 144-51？？
[55]
28 Chellappan P, Vanitharani R, Fauquet C M. Short Interfering RNA accumulation correlates with host recovery in DNA virus-Infected hosts,and gene silencing targets specific viral sequences. J Virol, 2004, 78: 7465-7477？？
[56]
29 Fusaro A F, Matthew L, Smith N A, et al. RNA interference-inducing hairpin RNAs in plants act through the viral defence pathway. EMBORep, 2006, 7:1168-1175？？
[57]
49 Hou W-N, Duan C-G, Fang R-X, et al. Satellite RNA reduces expression of the 2b suppressor protein resulting in the attenuation ofsymptoms caused by Cucumber mosaic virus infection. Mol Plant Pathol, 2011, 12: 595-605？？
[58]
50 Alvarado V, Scholthof H B. Plant responses against invasive nucleic acids: RNA silencing and its suppression by plant viral pathogens.Semin Cell Dev Biol, 2009, 20: 1032-40？？
[59]
51 Díaz-Pendón J A, Ding S W. Direct and indirect roles of viral suppressors of RNA silencing in pathogenesis. Annu Rev Phytopathol, 2008,46: 303-326？？
[60]
52 Dunoyer P, Voinnet O. The complex interplay between plant viruses and host RNA-silencing pathways. Curr Opin Plant Biol, 2005, 8:415-423？？
[61]
53 Wang M B. On the role of RNA silencing in the pathogenicity and evolution of viroids and viral satellites. Proc Natl Acad Sci USA, 2004,101: 3275-3280？？
[62]
54 Devic M, Jaegle M, Baulcombe D. Symptom production on tobacco and tomato is determined by two distinct domains of the satellite RNAof Cucumber mosaic virus (strain Y). J Gen Virol, 1989, 70: 2765-2774？？
[63]
55 Masuta C, Takanami Y. Determination of sequence and structural requirements for pathogenicity of a Cucumber mosaic virus satellite RNA(Y-satRNA). Plant Cell, 1989, 1: 1165-1173
[64]
56 Jaegle M, Devic M, Longstaff M, et al. Cucumber mosaic virus satellite RNA (Y strain): analysis of sequences which affect yellow mosaicsymptoms on tobacco. J Gen Virol, 1990, 71: 1905-1912？？
[65]
57 Kuwata S, Masuta C, Takanami Y. Reciprocal phenotype alterations between two satellite RNAs of cucumber mosaic virus. J Gen Virol,1991, 72: 2385-2389？？
[66]
58 Smith N A, Eamens A L, Wang M B. Viral small interfering RNAs target host genes to mediate disease symptoms in plants. PLoS Pathog,2011, 7: e1002022？？
[67]
59 Shimura H, Pantaleo V, Ishihara T, et al. A viral satellite RNA induces yellow symptoms on tobacco by targeting a gene involved inchlorophyll biosynthesis using the RNA silencing machinery. PLoS Pathog, 2011, 7: e1002021？？
