Normal and reversed phase thin-layer chromatography of new 16,17-secoestrone derivatives

The retention behaviour and separation ability of a series of new 16,17-secoestrone derivatives has been studied on silica gel, alumina and C-18 silica gel layers with non-aqueous and aqueous-organic mobile phases. The retention behavour and separation ability are discussed in terms of the nature of the solute, eluent and stationary phase.