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A note on the Noyori model for chiral amplification in the aminoalcohol-catalyzed reaction of aldehydes with dialkylzincKeywords: chiral stereoselection , chiral amplification , chiral catalysis , asymmetric synthesis Abstract: The Noyori model of chiral amplification in the alkylation of aldehydes by means of dialkylzinc, catalyzed by chiral aminoalcohols, is further elaborated. A direct, but approximate, relation is obtained between the enantiomeric excess of the catalyst added and the enantiomeric excess of the product.
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