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OALib Journal期刊
ISSN: 2333-9721
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A note on the Noyori model for chiral amplification in the aminoalcohol-catalyzed reaction of aldehydes with dialkylzinc

Keywords: chiral stereoselection , chiral amplification , chiral catalysis , asymmetric synthesis

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Abstract:

The Noyori model of chiral amplification in the alkylation of aldehydes by means of dialkylzinc, catalyzed by chiral aminoalcohols, is further elaborated. A direct, but approximate, relation is obtained between the enantiomeric excess of the catalyst added and the enantiomeric excess of the product.

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