Chemotherapy-induced nausea and vomiting: what are the best treatments

The treatment of chemotherapy-induced nausea and vomiting (CINV) has advanced considerably in recent years. The availability of the second-generation 5-HT3 receptor antagonist palonosetron and the NK1 receptor antagonists has significantly improved the clinical efficacy of anti-emesis. These drugs form a key part of the latest European (ESMO) guidelines on the best management of CINV.