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Synthesis of some pyridyl and cyclohexyl substituted 1,2,4 triazole, 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives

DOI: 10.5155/eurjchem.1.4.322-324.65

Keywords: 1 , 2 , 4-Triazole , 1 , 3 , 4-Thiadiazole , 1 , 3 , 4-Oxadiazole , Thiosemicarbazide

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Abstract:

New 1,2,4-triazoles (4a-c), 1,3,4-thiadiazoles (5a-c) and 1,3,4-oxadiazoles (6a-c) containing isomeric pyridyl and cyclohexyl were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides (3a-c) in alkaline media, acid and neutral condition respectively. The chemical structures of newly synthesized compounds were established with help of FT-IR, 1H-NMR and mass spectral data.

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