The Role Of Acute Phase Reactants In Acute Ischemic Stroke

Inflammatory factors play an important role in the pathogenesis of ischemic stroke. The aim of our study was to determine the influence of fibrinogen, C-reactive protein and other acute-phase reactant levels in acute ischemic stroke. This study involves forty -three patients. The control group was formed out of thirty-seven. The blood samples were drawn to measure serum fibrinogen, ferritin, CRP levels, white blood cell (WBC), erythrocyte sedimentation rate (ESR) within 24-72 hours, the patients serum fibrinogen, ferritin and CRP values were higher than the control group. In addition, the levels of fibrinogen and CRP were found to be higher than the patients whose clinical health was poor. Acute phase proteins level such a fibrinogen, CRP, ferritin increase after acute ischemic stroke. These findings support a possible role of an inflammatory stimulus in the acute ischemic stroke.