PATIENT COMPLIANCE IN DOTS BY HIV NON REACTIVE URBAN, SUBURBAN AND RURAL TUBERCULOSIS PATIENTS IN KARAD REGION

India accounts for one-fifth of the total global Tuberculosis (TB) incident cases. Each year more than 3,30,000 patients die due to TB. Recently it was found that due to multiple drug therapy, cases of non compliance are increasing. Nowadays TB and Human immunodeficiency virus (HIV) are most common, and are having high prevalence rate. Treatments to both diseases are having various multi-drug therapies; which may interact with each other. The main aim of study was to assess patient compliance rate and comparative assessment in Directly Observed Treatment, Short-course (DOTS) patients with focus on HIV non reactive cases in Karad region, Maharashtra state. The patient compliance was prospectively assessed in 202 individuals from urban, sub-urban and rural hospitals treated for TB. All were HIV non reactive cases. Of the 202 patients, 167 were compliant and 35 were non-compliant. Urban, sub-urban and rural had compliance rates of 79%, 92% and 81%, respectively. Due to various factors like adverse drug reactions, longer duration of the treatment etc. patient compliance to treatment decreases; which acts as one of the high risk factor for Multi-drug-resistant tuberculosis (MDR-TB).