Population mortality during the outbreak of Severe Acute Respiratory Syndrome in Toronto

Observational study of death registry data, using Poisson regression and interrupted time-series analysis to examine all-cause mortality rates (excluding deaths due to SARS) before, during, and after the SARS outbreak. The population of Ontario was grouped into the Greater Toronto Area (N = 2.9 million) and the rest of Ontario (N = 9.3 million) based upon the level of restrictions on delivery of clinical services during the SARS outbreak.There was no significant change in mortality in the Greater Toronto Area before, during, and after the period of the SARS outbreak in 2003 compared to the corresponding time periods in 2002 and 2001. The rate ratio for all-cause mortality during the SARS outbreak was 0.99 [95% Confidence Interval (CI) 0.93–1.06] compared to 2002 and 0.96 [95% CI 0.90–1.03] compared to 2001. An interrupted time series analysis found no significant change in mortality rates in the Greater Toronto Area associated with the period of the SARS outbreak.Limitations on access to medical services during the 2003 SARS outbreak in Toronto had no observable impact on short-term population mortality. Effects on morbidity and long-term mortality were not assessed. Efforts to contain future infectious disease outbreaks due to influenza or other agents must consider effects on access to essential health care services.In March 2003, the health care system in Toronto, Canada, was confronted with an outbreak of Severe Acute Respiratory Syndrome (SARS), a highly contagious and severe atypical pneumonia. [1-3] The infection control measures employed in response to this crisis were extraordinary and unprecedented. Actions to control SARS in the Greater Toronto Area included the closure of four hospitals, the cancellation of all non-emergency surgical services, an almost complete curtailment of inter-hospital patient transfers, and the postponement of most hospital-based outpatient clinics. [4,5] Moreover, access to physicians, hospital laboratories, imaging studies, and