Determination of Correction Factor Without Standard of Determined Compound
无需待测化合物标准样品便可测定校正因子

A new method of determining correction factor without standard of compounds to be determined is proposed. Two initial mixtures, which contain compounds to be determined, were mixed in different proportions. The mixed samples were analyzed by gas chromotagraphy. Based on the relationship of contents to the peak areas and correction factors, the correction factors were calculated by using optimization with Levenberg Marquardt method. In order to verify the present method, toluene chlorobenzene, diethoxymethane ethanol water and diethoxymethane ethyl acetate were analyzed separately. Experimental results show that relative deviations of the correction factors determined by the present method from those reported in literatures were less than 3%. The determined correction factors are suitable for quantitative analysis. As the present method is applied, it is suggested that the number of the compounds in the mixture should not be more than 3. When the number of parameters equals 2, the number of samples necessary should be in the range from 10 to 12. When the number equals 3, it should be in the range from 12 to 14. In addition, the difference of content of the same component in the initial mixtures must be great enough, i.e., more than 20%.