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色谱  2010 

Enantioseparation of 1,1''-bi-2-naphthol benzoates using high performance liquid chromatography
高效液相色谱法手性分离联萘二酚苯甲酸酯对映体

Keywords: high performance liquid chromatography (HPLC),enantioseparation,chiral stationary phase
高效液相色谱法
,对映体分离,手性固定相,联萘二酚苯甲酸酯

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Abstract:

The enantioseparations of 2'-hydroxy-1,1'-binaphthyl-2-yl benzoate(HBNB),1,1'-binaphthyl-2,2'-diyl dibenzoate(BNDB) and 2'-methoxy-1,1'-binaphthyl-2-yl benzoate(MBNB) were studied on Chirex(S)-LEU &(S)-NEA,cellulose tris(3,5-dimethylphenylcarbamate)(Chiralcel OD-H) and amylose tris(3,5-dimethylphenyl-carbamate)(Chiralpak AD-H) columns,respectively,using high performance liquid chromatography.The effects of mobile phase,column temperature and compound structures on the enantioseparations were discussed.The C...

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