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色谱 2010
Enantioseparation of 1,1''-bi-2-naphthol benzoates using high performance liquid chromatography
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Abstract:
The enantioseparations of 2'-hydroxy-1,1'-binaphthyl-2-yl benzoate(HBNB),1,1'-binaphthyl-2,2'-diyl dibenzoate(BNDB) and 2'-methoxy-1,1'-binaphthyl-2-yl benzoate(MBNB) were studied on Chirex(S)-LEU &(S)-NEA,cellulose tris(3,5-dimethylphenylcarbamate)(Chiralcel OD-H) and amylose tris(3,5-dimethylphenyl-carbamate)(Chiralpak AD-H) columns,respectively,using high performance liquid chromatography.The effects of mobile phase,column temperature and compound structures on the enantioseparations were discussed.The C...