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菌物学报  2004 

ANTITUMOR EFFECT OF GANODERIC ACID FROM GANODERMA LUCIDUM
灵芝中有效成分灵芝酸的抑制肿瘤作用研究

Keywords: NK cell,immunity,Lewis lung cancer,cell toxin
NK细胞
,免疫,Lewis肺癌,细胞毒

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Abstract:

Ganoderic acid has evident inhibiting effect on proliferation of tumor cells SW620, LS180, S180 in vitro, and curative effect on mice bearing Lewis lung cancer (toe inoculaion ). The promotive effect of Ganoderic acid on creating IL- 2 and immunoactive of NK cell in Guinea pig bearing Lewis lung cancer is also evident. It was suggested that the cancer-inhibiting effect was induced by Ganoderic acid through toxication of tumor cells and activation of immunity system.

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