INHIBITION OF RAT INTESTINE ESTERASE BY INSECTICIDES
农药混配剂对大鼠肠酯酶同工酶的抑制作用研究

The inhibition of rat intestine esterase by sumithion fenvalerate and NIA16388 has been studied in vivo and in vitro. The results showed that there are at least 10 esterase bands in rat intestine, most of which have carboxylesterase activity. Sumithion strongly inhibited the esterase activity at various treated durations, while the inhibition was found only at first two hours for fenvalerate and NIA16388. The degree of inhibition depended on insecticide dosage. The relationship between the inhibition of carboxylesterase and the toxicity of insecticide was discussed.