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Marine Drugs  2012 

New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae

DOI: 10.3390/md10020306

Keywords: Lobophytum michaelae, cembranolides, cytotoxicity

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Abstract:

Six new cembranolides, michaolides L–Q ( 1– 6), and a known cembranolide, lobomichaolide ( 7) were isolated from the CH 2Cl 2 extract of the soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The anti-HCMV (human cytomegalovirus) activity of 1– 7 and their cytotoxicity against selected cell lines were evaluated.

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