PREPARATION AND CHARACTERIZATION OF FAST-DISSOLVING ELECTROSPUN DRUG-LOADED PVP NANOFIBER MEMBRANES
速溶电纺载药PVP纳米纤维膜制备与表征

Drug-loaded nanofiber membrane was successfully prepared using electrospinning process with helicid as the poorly water-soluble model drug and polyvinylpyrrolidone(PVP K30) as the filament-forming matrix.Polarization microscopy(PM) and scanning electron microscopy(SEM) were taken to observe the morphology and structure of the nanofibers.Differential scanning calorimetry(DSC) and X-ray diffraction(XRD) were carried out to determine the physical status of the drug in the nanofibers.Fourier-transform infrared ...